Provera and Abnormal loss of weight - a phase IV clinical study of FDA data

Summary:

Abnormal loss of weight is reported as a side effect among people who take Provera (medroxyprogesterone acetate), especially for people who are male, 60+ old, also take Lipitor, and have Crohn's disease.

The phase IV clinical study analyzes which people have Abnormal loss of weight when taking Provera. It is created by eHealthMe based on reports of 53,365 people who have side effects when taking Provera from the FDA, and is updated regularly.

What is Provera?

Provera has active ingredients of medroxyprogesterone acetate. It is often used in birth control. eHealthMe is studying from 54,943 Provera users. Check the latest studies of Provera.

What is Abnormal loss of weight?

Abnormal loss of weight is found to be associated with 525 drugs and 878 conditions by eHealthMe. Check the latest studies of Abnormal loss of weight.



On Jul, 16, 2026

53,365 people reported to have side effects when taking Provera.
Among them, 16 people (0.03%) have Abnormal loss of weight.

Could Provera cause Abnormal loss of weight?

Among these 16 people:

What is the gender of people who have Abnormal loss of weight when taking Provera? *

  • female: 50 %
  • male: 50 %

What is the age of people who have Abnormal loss of weight when taking Provera? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 7.14 %
  • 30-39: 14.29 %
  • 40-49: 14.29 %
  • 50-59: 0.0 %
  • 60+: 64.29 %

What are other drugs people take besides Provera? *

  1. Zyrtec: 8 people, 50.00%
  2. Zometa: 8 people, 50.00%
  3. Avodart: 8 people, 50.00%
  4. Casodex: 8 people, 50.00%
  5. Celebrex: 8 people, 50.00%
  6. Dexamethasone: 8 people, 50.00%
  7. Flonase: 8 people, 50.00%
  8. Ketoconazole: 8 people, 50.00%
  9. Levaquin: 8 people, 50.00%
  10. Lipitor: 8 people, 50.00%

What are other side effects people have besides Abnormal loss of weight? *

  1. Joint Pain: 9 people, 56.25%
  2. Osteomyelitis (infection of bone): 8 people, 50.00%
  3. Bone Pain: 8 people, 50.00%
  4. Periodontitis (inflammation of the tissue around the teeth): 8 people, 50.00%
  5. Pain In Extremity: 8 people, 50.00%
  6. Pain: 8 people, 50.00%
  7. Osteoporosis (bones weak and more likely to break): 8 people, 50.00%
  8. Cataract (clouding of the lens inside the eye): 8 people, 50.00%
  9. Oral Pain: 8 people, 50.00%
  10. Prostate Cancer: 8 people, 50.00%

What are the existing conditions these people have? *

  1. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 3 people, 18.75%
  2. Uterine Leiomyoma (uterine benign tumour derived from smooth muscle): 1 person, 6.25%
  3. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 1 person, 6.25%
  4. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 6.25%
  5. Psoriasis (immune-mediated disease that affects the skin): 1 person, 6.25%
  6. Premature Menopause: 1 person, 6.25%
  7. Pain: 1 person, 6.25%
  8. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 1 person, 6.25%
  9. Metabolic Disorder (an abnormal function and pattern of body fat. insulin resistance refers to the diminished ability of cells to respond to the action of insulin in promoting the transport of the sugar glucose, from blood into muscles and other tissues): 1 person, 6.25%
  10. Kaposi's Sarcoma (a tumour caused by human herpes virus): 1 person, 6.25%

* Approximation only. Some reports may have incomplete information.

Do you take Provera and have Abnormal loss of weight?

- Check whether Abnormal loss of weight is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Provera:

Abnormal loss of weight treatments and more:

How severe was Abnormal loss of weight and when was it recovered:

Expand to all the drugs that have ingredients of medroxyprogesterone acetate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Provera:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Abnormal loss of weight:

Browse all the conditions that are associated with Abnormal loss of weight:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on medroxyprogesterone acetate (the active ingredients of Provera) and Provera (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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