Provera and Malabsorption - a phase IV clinical study of FDA data

Summary:

Malabsorption is reported as a side effect among people who take Provera (medroxyprogesterone acetate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Norvasc, and have High blood pressure.

The phase IV clinical study analyzes which people have Malabsorption when taking Provera. It is created by eHealthMe based on reports of 53,365 people who have side effects when taking Provera from the FDA, and is updated regularly.

What is Provera?

Provera has active ingredients of medroxyprogesterone acetate. It is often used in birth control. eHealthMe is studying from 54,943 Provera users. Check the latest studies of Provera.

What is Malabsorption?

Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract) is found to be associated with 704 drugs and 1,087 conditions by eHealthMe. Check the latest studies of Malabsorption.



On Jan, 11, 2026

53,365 people reported to have side effects when taking Provera.
Among them, 24 people (0.04%) have Malabsorption.

Could Provera cause Malabsorption?

Among these 24 people:

How long have people been on Provera when they have Malabsorption? *

  • < 1 month: 50 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 50 %

What is the gender of people who have Malabsorption when taking Provera? *

  • female: 95 %
  • male: 5 %

What is the age of people who have Malabsorption when taking Provera? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 5.88 %
  • 20-29: 5.88 %
  • 30-39: 17.65 %
  • 40-49: 11.76 %
  • 50-59: 17.65 %
  • 60+: 41.18 %

What are other drugs people take besides Provera? *

  1. Norvasc: 8 people, 33.33%
  2. Flonase: 6 people, 25.00%
  3. Premarin: 6 people, 25.00%
  4. Benicar Hct: 6 people, 25.00%
  5. Benicar: 6 people, 25.00%
  6. Synthroid: 5 people, 20.83%
  7. Ativan: 4 people, 16.67%
  8. Wellbutrin: 4 people, 16.67%
  9. Singulair: 4 people, 16.67%
  10. Prochlorperazine: 3 people, 12.50%

What are other side effects people have besides Malabsorption? *

  1. Insomnia (sleeplessness): 9 people, 37.50%
  2. Dizziness: 9 people, 37.50%
  3. Gallstones (stone formation by bile component): 8 people, 33.33%
  4. Nausea (feeling of having an urge to vomit): 7 people, 29.17%
  5. Weakness: 7 people, 29.17%
  6. Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 7 people, 29.17%
  7. Hypotension (abnormally low blood pressure): 6 people, 25.00%
  8. Joint Pain: 6 people, 25.00%
  9. Drug-Induced Liver Injury (diseases of the liver that are caused by physician-prescribed medications): 6 people, 25.00%
  10. Thrombocytopenia (decrease of platelets in blood): 6 people, 25.00%

What are the existing conditions these people have? *

  1. High Blood Pressure: 8 people, 33.33%
  2. Pain: 3 people, 12.50%
  3. Osteoporosis (bones weak and more likely to break): 3 people, 12.50%
  4. Osteopenia (a condition where bone mineral density is lower than normal): 3 people, 12.50%
  5. Menopause (end of monthly cycles in women): 2 people, 8.33%
  6. Menopausal Symptoms: 2 people, 8.33%
  7. Gastric Disorder (disease of stomach): 2 people, 8.33%
  8. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 8.33%
  9. Bone Disorder: 2 people, 8.33%
  10. Impaired Gastric Emptying: 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Provera and have Malabsorption?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Provera:

Malabsorption treatments and more:

How severe was Malabsorption and when was it recovered:

Expand to all the drugs that have ingredients of medroxyprogesterone acetate:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Provera:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Malabsorption:

Browse all the conditions that are associated with Malabsorption:

Drugs similar to Provera and Malabsorption :

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on medroxyprogesterone acetate (the active ingredients of Provera) and Provera (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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