Prozac and Akinesia - a phase IV clinical study of FDA data

Summary:

Akinesia is reported as a side effect among people who take Prozac (fluoxetine hydrochloride), especially for people who are male, 20-29 old, have been taking the drug for < 1 month also take Zoloft, and have Bipolar disorder.

The phase IV clinical study analyzes which people have Akinesia when taking Prozac. It is created by eHealthMe based on reports of 74,788 people who have side effects when taking Prozac from the FDA, and is updated regularly.

What is Prozac?

Prozac has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 82,988 Prozac users. Check the latest studies of Prozac.

What is Akinesia?

Akinesia (loss of control of voluntary muscle movements) is found to be associated with 304 drugs and 483 conditions by eHealthMe. Check the latest studies of Akinesia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 31, 2026

74,788 people reported to have side effects when taking Prozac.
Among them, 18 people (0.02%) have Akinesia.

Could Prozac cause Akinesia?

Among these 18 people:

How long have people been on Prozac when they have Akinesia? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Akinesia when taking Prozac? *

  • female: 38.89 %
  • male: 61.11 %

What is the age of people who have Akinesia when taking Prozac? *

  • 0-1: 0.0 %
  • 2-9: 6.67 %
  • 10-19: 6.67 %
  • 20-29: 33.33 %
  • 30-39: 20.0 %
  • 40-49: 13.33 %
  • 50-59: 13.33 %
  • 60+: 6.67 %

What are other drugs people take besides Prozac? *

  1. Abilify: 5 people, 27.78%
  2. Zoloft: 5 people, 27.78%
  3. Celexa: 4 people, 22.22%
  4. Wellbutrin: 4 people, 22.22%
  5. Depakote: 4 people, 22.22%
  6. Geodon: 4 people, 22.22%
  7. Paxil: 3 people, 16.67%
  8. Cymbalta: 3 people, 16.67%
  9. Effexor: 3 people, 16.67%
  10. Klonopin: 3 people, 16.67%

What are other side effects people have besides Akinesia? *

  1. Drug Ineffective: 5 people, 27.78%
  2. Drowsiness: 4 people, 22.22%
  3. Thrombocytopenia (decrease of platelets in blood): 4 people, 22.22%
  4. Fatigue (feeling of tiredness): 4 people, 22.22%
  5. Tremor (trembling or shaking movements in one or more parts of your body): 3 people, 16.67%
  6. Dizziness: 3 people, 16.67%
  7. Platelet Count Increased: 3 people, 16.67%
  8. Drug Withdrawal Syndrome (interfere with normal social, occupational, or other functioning. are not due to another medical condition, drug use, or discontinuation): 2 people, 11.11%
  9. Movement - Uncoordinated: 2 people, 11.11%
  10. Drug Dependence: 2 people, 11.11%

What are the existing conditions these people have? *

  1. Bipolar Disorder (mood disorder): 3 people, 16.67%
  2. Parkinson's Disease: 2 people, 11.11%
  3. Pain: 2 people, 11.11%
  4. Panic Disorder: 1 person, 5.56%
  5. Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 1 person, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Prozac and have Akinesia?

- Check whether Akinesia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prozac:

Akinesia treatments and more:

How severe was Akinesia and when was it recovered:

Expand to all the drugs that have ingredients of fluoxetine hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prozac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Akinesia:

Browse all the conditions that are associated with Akinesia:


How the study uses the data?

The study uses data from the FDA. It is based on fluoxetine hydrochloride (the active ingredients of Prozac) and Prozac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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