Prozac and Orgasmic dysfunction - a phase IV clinical study of FDA data

Summary:

Orgasmic dysfunction is reported as a side effect among people who take Prozac (fluoxetine hydrochloride), especially for people who are 60+ old, have been taking the drug for 1 - 2 years also take Sertraline, and have Depression suicidal.

The phase IV clinical study analyzes which people have Orgasmic dysfunction when taking Prozac. It is created by eHealthMe based on reports of 74,788 people who have side effects when taking Prozac from the FDA, and is updated regularly.

What is Prozac?

Prozac has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 82,986 Prozac users. Check the latest studies of Prozac.

What is Orgasmic dysfunction?

Orgasmic dysfunction (not getting orgasm) is found to be associated with 244 drugs and 562 conditions by eHealthMe. Check the latest studies of Orgasmic dysfunction.

On Apr, 10, 2026

74,788 people reported to have side effects when taking Prozac.
Among them, 61 people (0.08%) have Orgasmic dysfunction.

Could Prozac cause Orgasmic dysfunction?

Among these 61 people:

How long have people been on Prozac when they have Orgasmic dysfunction? *

What is the age of people who have Orgasmic dysfunction when taking Prozac? *

What are other drugs people take besides Prozac? *

What are other side effects people have besides Orgasmic dysfunction? *

Erection Problems: 27 people, 44.26%
Libido Decreased (loss of interest in sex): 22 people, 36.07%
Drug Ineffective: 12 people, 19.67%
Penis Disorder: 10 people, 16.39%
Fatigue (feeling of tiredness): 9 people, 14.75%
Loss Of Libido (loss of sexual urge): 7 people, 11.48%
Weight Increased: 7 people, 11.48%
Feeling Abnormal: 5 people, 8.20%
Sleep Disorder: 4 people, 6.56%
Confusional State: 4 people, 6.56%

What are the existing conditions these people have? *

Depression Suicidal (suicide depressive disorder): 10 people, 16.39%
Obsessive-Compulsive Disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;): 2 people, 3.28%
Erection Problems: 2 people, 3.28%
Urinary Tract Infection: 1 person, 1.64%
Suicidal Ideation: 1 person, 1.64%
Sleep Disorder: 1 person, 1.64%
Sinusitis (inflammation of sinus): 1 person, 1.64%
Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 1 person, 1.64%
Initial Insomnia (feeling of inadequate or poor-quality sleep): 1 person, 1.64%
Hypersensitivity: 1 person, 1.64%

* Approximation only. Some reports may have incomplete information.

Do you take Prozac and have Orgasmic dysfunction?

- Check whether Orgasmic dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prozac:

Prozac (82,986 reports)

Browse all side effects of Prozac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Orgasmic dysfunction:

Orgasmic dysfunction (244 drugs)

Browse all the conditions that are associated with Orgasmic dysfunction:

Orgasmic dysfunction (562 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on fluoxetine hydrochloride (the active ingredients of Prozac) and Prozac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.