Prozac and Pericarditis - a phase IV clinical study of FDA data

Summary:

Pericarditis is reported as a side effect among people who take Prozac (fluoxetine hydrochloride), especially for people who are female, 50-59 old, have been taking the drug for 2 - 5 years also take Neurontin, and have Multiple sclerosis.

The phase IV clinical study analyzes which people have Pericarditis when taking Prozac. It is created by eHealthMe based on reports of 74,788 people who have side effects when taking Prozac from the FDA, and is updated regularly.

What is Prozac?

Prozac has active ingredients of fluoxetine hydrochloride. It is often used in depression. eHealthMe is studying from 82,977 Prozac users. Check the latest studies of Prozac.

What is Pericarditis?

Pericarditis (inflammation of the pericardium) is found to be associated with 896 drugs and 935 conditions by eHealthMe. Check the latest studies of Pericarditis.



On Dec, 09, 2025

74,788 people reported to have side effects when taking Prozac.
Among them, 64 people (0.09%) have Pericarditis.

Could Prozac cause Pericarditis?

Among these 64 people:

How long have people been on Prozac when they have Pericarditis? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 100 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Pericarditis when taking Prozac? *

  • female: 77.78 %
  • male: 22.22 %

What is the age of people who have Pericarditis when taking Prozac? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 3.45 %
  • 30-39: 12.07 %
  • 40-49: 24.14 %
  • 50-59: 32.76 %
  • 60+: 27.59 %

What are other drugs people take besides Prozac? *

  1. Neurontin: 11 people, 17.19%
  2. Zocor: 10 people, 15.62%
  3. Remeron: 10 people, 15.62%
  4. Avapro: 9 people, 14.06%
  5. Provigil: 9 people, 14.06%
  6. Restasis: 9 people, 14.06%
  7. Naprosyn: 9 people, 14.06%
  8. Ditropan Xl: 9 people, 14.06%
  9. Synthroid: 9 people, 14.06%
  10. Levoxyl: 9 people, 14.06%

What are other side effects people have besides Pericarditis? *

  1. Fatigue (feeling of tiredness): 19 people, 29.69%
  2. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 16 people, 25.00%
  3. Chest Pain: 16 people, 25.00%
  4. Pericardial Effusion (fluid around the heart): 15 people, 23.44%
  5. Anaemia (lack of blood): 14 people, 21.88%
  6. Dyspnea (difficult or laboured breathing): 14 people, 21.88%
  7. Cough: 14 people, 21.88%
  8. Sleep Disorder: 13 people, 20.31%
  9. Abdominal Pain Upper: 10 people, 15.62%
  10. Joint Pain: 8 people, 12.50%

What are the existing conditions these people have? *

  1. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 12 people, 18.75%
  2. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 6.25%
  3. Constipation: 3 people, 4.69%
  4. Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 3.12%
  5. Pneumonia: 2 people, 3.12%
  6. High Blood Pressure: 2 people, 3.12%
  7. Dysaesthesia (abnormal sensation): 2 people, 3.12%
  8. Drowsiness: 2 people, 3.12%
  9. Tremor (trembling or shaking movements in one or more parts of your body): 2 people, 3.12%
  10. Lung Cancer - Non-Small Cell (lung cancer): 2 people, 3.12%

* Approximation only. Some reports may have incomplete information.

Do you take Prozac and have Pericarditis?

- Check whether Pericarditis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Prozac:

Pericarditis treatments and more:

How severe was Pericarditis and when was it recovered:

Expand to all the drugs that have ingredients of fluoxetine hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prozac:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pericarditis:

Browse all the conditions that are associated with Pericarditis:

Drugs similar to Prozac and Pericarditis :


How the study uses the data?

The study uses data from the FDA. It is based on fluoxetine hydrochloride (the active ingredients of Prozac) and Prozac (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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