1. Home
  2. Analysis
  3. Purinethol
  4. Acne

Purinethol and Acne - a phase IV clinical study of FDA data

Summary:

Acne is reported as a side effect among people who take Purinethol (mercaptopurine), especially for people who are female, 40-49 old, also take Inflectra, and have Menopause.

The phase IV clinical study analyzes which people have Acne when taking Purinethol. It is created by eHealthMe based on reports of 3,767 people who have side effects when taking Purinethol from the FDA, and is updated regularly.

What is Purinethol?

Purinethol has active ingredients of mercaptopurine. It is often used in ulcerative colitis. eHealthMe is studying from 3,810 Purinethol users. Check the latest studies of Purinethol.

What is Acne?

Acne (skin problems that cause pimples) is found to be associated with 1,313 drugs and 2,344 conditions by eHealthMe. Check the latest studies of Acne.

On Jul, 15, 2026

3,767 people reported to have side effects when taking Purinethol.
Among them, 31 people (0.82%) have Acne.

Could Purinethol cause Acne?

Among these 31 people:

What is the gender of people who have Acne when taking Purinethol? *

  • female: 93.75 %
  • male: 6.25 %

What is the age of people who have Acne when taking Purinethol? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 6.25 %
  • 20-29: 25.0 %
  • 30-39: 6.25 %
  • 40-49: 43.75 %
  • 50-59: 0.0 %
  • 60+: 18.75 %

What are other drugs people take besides Purinethol? *

  1. Inflectra: 14 people, 45.16%
  2. Ultram: 9 people, 29.03%
  3. Colestid: 9 people, 29.03%
  4. Dexilant: 9 people, 29.03%
  5. Calcium: 8 people, 25.81%
  6. Vitamin C: 8 people, 25.81%
  7. Ramipril: 4 people, 12.90%
  8. Methylprednisolone: 4 people, 12.90%
  9. Estradiol: 4 people, 12.90%
  10. Pentasa: 3 people, 9.68%

What are other side effects people have besides Acne? *

  1. Nasopharyngitis (inflammation of the nasopharynx): 20 people, 64.52%
  2. Itching: 19 people, 61.29%
  3. Fatigue (feeling of tiredness): 18 people, 58.06%
  4. Headache (pain in head): 14 people, 45.16%
  5. Rashes (redness): 14 people, 45.16%
  6. Weight Increased: 13 people, 41.94%
  7. Abdominal Pain: 13 people, 41.94%
  8. Dizziness: 11 people, 35.48%
  9. Joint Pain: 11 people, 35.48%
  10. Haematochezia (passage of stools containing blood): 10 people, 32.26%

What are the existing conditions these people have? *

  1. Menopause (end of monthly cycles in women): 8 people, 25.81%
  2. Pain: 4 people, 12.90%
  3. Indigestion: 2 people, 6.45%
  4. Stress And Anxiety: 1 person, 3.23%
  5. Insomnia (sleeplessness): 1 person, 3.23%
  6. Dry Mouth: 1 person, 3.23%
  7. Acne Cystic (skin problems that cause pimples): 1 person, 3.23%

* Approximation only. Some reports may have incomplete information.

Do you take Purinethol and have Acne?

- Check whether Acne is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Purinethol:

Acne treatments and more:

  • Acne (179,011 reports)

How severe was Acne and when was it recovered:

Expand to all the drugs that have ingredients of mercaptopurine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Purinethol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Acne:

  • Acne (1,313 drugs)

Browse all the conditions that are associated with Acne:

  • Acne (2,344 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on mercaptopurine (the active ingredients of Purinethol) and Purinethol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

Recent studies on eHealthMe:

© 2026 eHealthMe.com. All rights reserved. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy.