Purinethol and Arrhythmias - a phase IV clinical study of FDA data
Summary:
Arrhythmias is reported as a side effect among people who take Purinethol (mercaptopurine), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Inflectra, and have Acute lymphocytic leukemia (all).
The phase IV clinical study analyzes which people have Arrhythmias when taking Purinethol. It is created by eHealthMe based on reports of 3,767 people who have side effects when taking Purinethol from the FDA, and is updated regularly.
What is Purinethol?
Purinethol has active ingredients of mercaptopurine. It is often used in ulcerative colitis. eHealthMe is studying from 3,810 Purinethol users. Check the latest studies of Purinethol.
What is Arrhythmias?
Arrhythmias (irregular heartbeat) is found to be associated with 2,757 drugs and 4,837 conditions by eHealthMe. Check the latest studies of Arrhythmias.
3,767 people reported to have side effects when taking Purinethol.
Among them, 49 people (1.3%) have Arrhythmias.

Among these 49 people:
How long have people been on Purinethol when they have Arrhythmias? *
- < 1 month: 100 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Arrhythmias when taking Purinethol? *
- female: 64.86 %
- male: 35.14 %
What is the age of people who have Arrhythmias when taking Purinethol? *
- 0-1: 2.78 %
- 2-9: 5.56 %
- 10-19: 16.67 %
- 20-29: 13.89 %
- 30-39: 8.33 %
- 40-49: 25.0 %
- 50-59: 5.56 %
- 60+: 22.22 %
What are other drugs people take besides Purinethol? *
- Methotrexate: 10 people, 20.41%
- Inflectra: 10 people, 20.41%
- Remicade: 8 people, 16.33%
- Vfend: 8 people, 16.33%
- Flagyl: 7 people, 14.29%
- Prednisone: 7 people, 14.29%
- Augmentin: 6 people, 12.24%
- Hydrea: 6 people, 12.24%
- Cancidas: 5 people, 10.20%
- Acetaminophen: 4 people, 8.16%
What are other side effects people have besides Arrhythmias? *
- Fatigue (feeling of tiredness): 20 people, 40.82%
- Fever: 19 people, 38.78%
- Cough: 13 people, 26.53%
- Dyspnea (difficult or laboured breathing): 12 people, 24.49%
- Nausea (feeling of having an urge to vomit): 9 people, 18.37%
- Headache (pain in head): 9 people, 18.37%
- Haematochezia (passage of stools containing blood): 8 people, 16.33%
- Speech Disorder: 8 people, 16.33%
- High Blood Pressure: 7 people, 14.29%
- Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 7 people, 14.29%
What are the existing conditions these people have? *
- Urination - Painful: 4 people, 8.16%
- Hepatitis C: 4 people, 8.16%
- Autoimmune Hepatitis: 4 people, 8.16%
- Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 4 people, 8.16%
- Bronchopulmonary Aspergillosis (lung disorder caused by aspergillus fungi): 3 people, 6.12%
- Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 3 people, 6.12%
- High Blood Pressure: 2 people, 4.08%
- Ankylosing Spondylitis (type of arthritis affecting the spine): 2 people, 4.08%
- Type 2 Diabetes: 1 person, 2.04%
- T-Cell Type Acute Leukaemia (a form of cancer of the white blood cells): 1 person, 2.04%
* Approximation only. Some reports may have incomplete information.
Do you take Purinethol and have Arrhythmias?
- Check whether Arrhythmias is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Purinethol:
- Purinethol (3,810 reports)
Arrhythmias treatments and more:
- Arrhythmias (177,908 reports)
How severe was Arrhythmias and when was it recovered:
Expand to all the drugs that have ingredients of mercaptopurine:
- Arrhythmias and drugs with ingredients of mercaptopurine (315 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Purinethol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Arrhythmias:
- Arrhythmias (2,757 drugs)
Browse all the conditions that are associated with Arrhythmias:
- Arrhythmias (4,837 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on mercaptopurine (the active ingredients of Purinethol) and Purinethol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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