Purinethol and Chronic obstructive pulmonary disease - a phase IV clinical study of FDA data

Summary:

Chronic obstructive pulmonary disease is reported as a side effect among people who take Purinethol (mercaptopurine), especially for people who are female, 50-59 old, also take Humira, and have Ankylosing spondylitis.

The phase IV clinical study analyzes which people have Chronic obstructive pulmonary disease when taking Purinethol. It is created by eHealthMe based on reports of 3,767 people who have side effects when taking Purinethol from the FDA, and is updated regularly.

What is Purinethol?

Purinethol has active ingredients of mercaptopurine. It is often used in ulcerative colitis. eHealthMe is studying from 3,810 Purinethol users. Check the latest studies of Purinethol.

What is Chronic obstructive pulmonary disease?

Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe) is found to be associated with 1,801 drugs and 2,209 conditions by eHealthMe. Check the latest studies of Chronic obstructive pulmonary disease.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 22, 2026

3,767 people reported to have side effects when taking Purinethol.
Among them, 11 people (0.29%) have Chronic obstructive pulmonary disease.

Could Purinethol cause Chronic obstructive pulmonary disease?

Among these 11 people:

What is the gender of people who have Chronic obstructive pulmonary disease when taking Purinethol? *

female: 70 %
male: 30 %

What is the age of people who have Chronic obstructive pulmonary disease when taking Purinethol? *

What are other drugs people take besides Purinethol? *

What are other side effects people have besides Chronic obstructive pulmonary disease? *

Generalized Anxiety Disorder (excessive, uncontrollable, unexplained and often irrational worry): 7 people, 63.64%
Irritability: 7 people, 63.64%
Borderline Personality Disorder: 7 people, 63.64%
C-Reactive Protein Increased: 7 people, 63.64%
Colitis (inflammation of colon): 7 people, 63.64%
Drug Ineffective: 7 people, 63.64%
Drug Intolerance (drug sensitivity): 7 people, 63.64%
Entero-Enteral Or Enterocutaneous Fistula: 7 people, 63.64%
Flatulence (flatus expelled through the anus): 7 people, 63.64%
Gastritis Erosive (a break in the surface layer of the membrane lining the stomach with infection): 7 people, 63.64%

What are the existing conditions these people have? *

Uveitis (inflammation of the uvea): 1 person, 9.09%
Productive Cough: 1 person, 9.09%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 9.09%
High Blood Pressure: 1 person, 9.09%
High Blood Cholesterol: 1 person, 9.09%
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 1 person, 9.09%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 9.09%
Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Purinethol and have Chronic obstructive pulmonary disease?

- Check whether Chronic obstructive pulmonary disease is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Purinethol:

Purinethol (3,810 reports)

Browse all side effects of Purinethol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Chronic obstructive pulmonary disease:

Chronic obstructive pulmonary disease (1,801 drugs)

Browse all the conditions that are associated with Chronic obstructive pulmonary disease:

Chronic obstructive pulmonary disease (2,209 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on mercaptopurine (the active ingredients of Purinethol) and Purinethol (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.