Pylera and Fatigue - a phase IV clinical study of FDA data

Summary:

Fatigue is reported as a side effect among people who take Pylera (bismuth subcitrate potassium; metronidazole; tetracycline), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Isentress, and have Helicobacter infection.

The phase IV clinical study analyzes which people have Fatigue when taking Pylera. It is created by eHealthMe based on reports of 1,008 people who have side effects when taking Pylera from the FDA, and is updated regularly.

What is Pylera?

Pylera has active ingredients of bismuth subcitrate potassium; metronidazole; tetracycline. eHealthMe is studying from 1,036 Pylera users. Check the latest studies of Pylera.

What is Fatigue?

Fatigue (feeling of tiredness) is found to be associated with 4,026 drugs and 6,380 conditions by eHealthMe. Check the latest studies of Fatigue.



On Jul, 21, 2026

1,008 people reported to have side effects when taking Pylera.
Among them, 51 people (5.06%) have Fatigue.

Could Pylera cause Fatigue?

Among these 51 people:

How long have people been on Pylera when they have Fatigue? *

  • < 1 month: 93.94 %
  • 1 - 6 months: 3.03 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 3.03 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Fatigue when taking Pylera? *

  • female: 70.59 %
  • male: 29.41 %

What is the age of people who have Fatigue when taking Pylera? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 10.53 %
  • 30-39: 13.16 %
  • 40-49: 10.53 %
  • 50-59: 28.95 %
  • 60+: 36.84 %

What are other drugs people take besides Pylera? *

  1. Cymbalta: 4 people, 7.84%
  2. Truvada: 4 people, 7.84%
  3. Omeprazole: 4 people, 7.84%
  4. Pantoprazole: 4 people, 7.84%
  5. Isentress: 4 people, 7.84%
  6. Zolpidem: 3 people, 5.88%
  7. Pegasys: 3 people, 5.88%
  8. Mycobutin: 3 people, 5.88%
  9. Copegus: 3 people, 5.88%
  10. Ofev: 2 people, 3.92%

What are other side effects people have besides Fatigue? *

  1. Dizziness: 20 people, 39.22%
  2. Headache (pain in head): 17 people, 33.33%
  3. Nausea (feeling of having an urge to vomit): 13 people, 25.49%
  4. Faeces Discolored: 11 people, 21.57%
  5. Weakness: 10 people, 19.61%
  6. Nausea And Vomiting: 10 people, 19.61%
  7. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 10 people, 19.61%
  8. Diarrhea: 9 people, 17.65%
  9. Stress And Anxiety: 8 people, 15.69%
  10. Weight Decreased: 8 people, 15.69%

What are the existing conditions these people have? *

  1. Helicobacter Infection (helicobacter pylori (h. pylori) infects stomach): 26 people, 50.98%
  2. Gastric Ulcer (stomach ulcer): 2 people, 3.92%
  3. Multiple Myeloma (cancer of the plasma cells): 2 people, 3.92%
  4. Idiopathic Pulmonary Fibrosis (chronic lung disease): 2 people, 3.92%
  5. Hiv Infection: 2 people, 3.92%
  6. Thyroid Diseases: 1 person, 1.96%
  7. Helicobacter Gastritis (inflammation of the inner lining of the stomach caused by helicobacter pylori (h. pylori) a bacterium): 1 person, 1.96%
  8. Bacterial Infection: 1 person, 1.96%
  9. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 1.96%
  10. Gastric Disorder (disease of stomach): 1 person, 1.96%

* Approximation only. Some reports may have incomplete information.

Do you take Pylera and have Fatigue?

- Check whether Fatigue is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pylera:

Fatigue treatments and more:

How severe was Fatigue and when was it recovered:

Expand to all the drugs that have ingredients of bismuth subcitrate potassium; metronidazole; tetracycline:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pylera:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Fatigue:

Browse all the conditions that are associated with Fatigue:

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on bismuth subcitrate potassium; metronidazole; tetracycline (the active ingredients of Pylera) and Pylera (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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