Pyridium and Heart attack - a phase IV clinical study of FDA data

Summary:

Heart attack is reported as a side effect among people who take Pyridium (phenazopyridine hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Protonix, and have Asthma.

The phase IV clinical study analyzes which people have Heart attack when taking Pyridium. It is created by eHealthMe based on reports of 1,694 people who have side effects when taking Pyridium from the FDA, and is updated regularly.

What is Pyridium?

Pyridium has active ingredients of phenazopyridine hydrochloride. It is often used in urinary tract infection. eHealthMe is studying from 1,841 Pyridium users. Check the latest studies of Pyridium.

What is Heart attack?

Heart attack is found to be associated with 2,538 drugs and 3,270 conditions by eHealthMe. Check the latest studies of Heart attack.

On Oct, 22, 2025

1,694 people reported to have side effects when taking Pyridium.
Among them, 21 people (1.24%) have Heart attack.

Among these 21 people:

How long have people been on Pyridium when they have Heart attack? *

What is the gender of people who have Heart attack when taking Pyridium? *

female: 95 %
male: 5 %

What is the age of people who have Heart attack when taking Pyridium? *

What are other drugs people take besides Pyridium? *

What are other side effects people have besides Heart attack? *

Fall: 11 people, 52.38%
Pain: 10 people, 47.62%
Asthma: 10 people, 47.62%
Arrhythmias (irregular heartbeat): 9 people, 42.86%
Upper Limb Fracture: 9 people, 42.86%
Vision Blurred: 9 people, 42.86%
Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 9 people, 42.86%
Lip Swelling: 9 people, 42.86%
Dizziness: 9 people, 42.86%
Swelling: 9 people, 42.86%

What are the existing conditions these people have? *

Abdominal Discomfort: 9 people, 42.86%
Cardiac Disorder: 9 people, 42.86%
Hypersensitivity: 9 people, 42.86%
Chest Pain: 9 people, 42.86%
Pain: 9 people, 42.86%
Asthma: 9 people, 42.86%
Sensory Disturbance (sense disturbance): 8 people, 38.10%
Trigeminal Neuralgia (a painful condition of the nerve responsible for most facial sensation): 8 people, 38.10%
Cerebral Disorder (brain disease): 7 people, 33.33%
Diabetes: 4 people, 19.05%

* Approximation only. Some reports may have incomplete information.

Do you take Pyridium and have Heart attack?

- Check whether Heart attack is associated with a drug or a condition (FREE)
- Predict drug outcomes for up to one year with AI (FREE)
- Get an AI agent to monitor your drugs continuously (FREE)

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pyridium:

Pyridium (1,841 reports)

Heart attack treatments and more:

Heart attack (266,139 reports)

Browse all side effects of Pyridium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Heart attack:

Heart attack (2,538 drugs)

Browse all the conditions that are associated with Heart attack:

Heart attack (3,270 conditions)

Drugs similar to Pyridium and Heart attack :

How the study uses the data?

The study uses data from the FDA. It is based on phenazopyridine hydrochloride (the active ingredients of Pyridium) and Pyridium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.