Pyridoxal and Death - a phase IV clinical study of FDA data

Summary:

Death is reported as a side effect among people who take Pyridoxal (pyridoxine (vitamin b6)), especially for people who are female, 60+ old, also take Prednisolone, and have Rheumatoid arthritis.

The study is created by eHealthMe based on reports of 1,018 people who have side effects when taking Pyridoxal from the FDA, and is updated regularly.

What is Pyridoxal?

Pyridoxal has active ingredients of pyridoxine (vitamin b6). eHealthMe is studying from 1,025 Pyridoxal users. Check the latest studies of Pyridoxal.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

1,018 people reported to have side effects when taking Pyridoxal.
Among them, 15 people (1.47%) died.

Among these 15 people:

What is the gender of people who died when taking Pyridoxal? *

female: 57.14 %
male: 42.86 %

What is the age of people who died when taking Pyridoxal? *

What are other drugs people take besides Pyridoxal? *

Prednisolone: 4 people, 26.67%
Lansoprazole: 3 people, 20.00%
Sulfamethoxazole And Trimethoprim: 2 people, 13.33%
Isoniazid: 2 people, 13.33%
Lasix: 2 people, 13.33%
Halaven: 2 people, 13.33%
Methotrexate: 2 people, 13.33%
Folic Acid: 2 people, 13.33%
Nexium: 2 people, 13.33%
Nifedipine: 2 people, 13.33%

What are other side effects people have before they died? *

Osteonecrosis Of Jaw (death of bone of jaw): 3 people, 20.00%
Anaemia (lack of blood): 3 people, 20.00%
Gastric Ulcer (stomach ulcer): 2 people, 13.33%
Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung): 2 people, 13.33%
Musculoskeletal Pain (pain affects the bones, muscles, ligaments, tendons, and nerves): 2 people, 13.33%
Bronchopleural Fistula: 2 people, 13.33%
Dizziness: 2 people, 13.33%
Dizziness Postural: 2 people, 13.33%
Infectious Pleural Effusion (infectious fluid in the lung): 2 people, 13.33%
Back Pain: 2 people, 13.33%

What are the existing conditions these people have? *

Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 33.33%
Multiple Myeloma (cancer of the plasma cells): 3 people, 20.00%
Metastases To Bone (cancer spreads to bone): 3 people, 20.00%
Insomnia (sleeplessness): 2 people, 13.33%
Tonic Convulsion (the person will quickly lose consciousness and the skeletal muscles will suddenly tense, often causing the extremities to be pulled towards the body or rigidly pushed away from it): 1 person, 6.67%
Gastric Cancer (stomach cancer): 1 person, 6.67%
Colon Cancer Metastatic (cancer of colon spreads to other part of body): 1 person, 6.67%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 1 person, 6.67%
Diabetes: 1 person, 6.67%
Disease Complication: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Pyridoxal:

Pyridoxal (1,025 reports)

Expand to all the drugs that have ingredients of pyridoxine (vitamin b6):

Death and drugs with ingredients of pyridoxine (vitamin b6) (331 reports)

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Pyridoxal:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Death:

Death (3,113 drugs)

Browse all the conditions that are associated with Death:

Death (3,686 conditions)

Related publications that referenced our studies

Hassan JK, "POTENTIAL POSITIVE EFFECT OF ORAL PYRIDOXINE ALONE AND IN COMBINATION WITH MECLIZINE ON CIGARETTES SMOKING DURING TENDAYS’TRIAL", IJPSR, 2015 Jan .
Hassan JK, "POTENTIAL POSITIVE EFFECT OF ORAL PYRIDOXINE ALONE AND IN COMBINATION WITH MECLIZINE ON CIGARETTES SMOKING DURING TENDAYS’TRIAL", IJPSR, 2015 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on pyridoxine (vitamin b6) (the active ingredients of Pyridoxal) and Pyridoxal (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.