Qsymia and Poor quality sleep - a phase IV clinical study of FDA data

Summary:

Poor quality sleep is reported as a side effect among people who take Qsymia (phentermine hydrochloride; topiramate), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Armour Thyroid, and have Weight decreased.

The phase IV clinical study analyzes which people have Poor quality sleep when taking Qsymia. It is created by eHealthMe based on reports of 4,445 people who have side effects when taking Qsymia from the FDA, and is updated regularly.

What is Qsymia?

Qsymia has active ingredients of phentermine hydrochloride; topiramate. It is often used in weight loss. eHealthMe is studying from 4,530 Qsymia users. Check the latest studies of Qsymia.

What is Poor quality sleep?

Poor quality sleep is found to be associated with 1,264 drugs and 1,163 conditions by eHealthMe. Check the latest studies of Poor quality sleep.

On Jul, 10, 2026

4,445 people reported to have side effects when taking Qsymia.
Among them, 12 people (0.27%) have Poor quality sleep.

Among these 12 people:

How long have people been on Qsymia when they have Poor quality sleep? *

What is the gender of people who have Poor quality sleep when taking Qsymia? *

female: 83.33 %
male: 16.67 %

What is the age of people who have Poor quality sleep when taking Qsymia? *

What are other drugs people take besides Qsymia? *

What are other side effects people have besides Poor quality sleep? *

Dry Mouth: 3 people, 25.00%
Taste - Impaired: 2 people, 16.67%
Hypoaesthesia (reduced sense of touch or sensation): 2 people, 16.67%
Depressed Mood: 2 people, 16.67%
Fatigue (feeling of tiredness): 2 people, 16.67%
Feeling Jittery: 2 people, 16.67%
Headache (pain in head): 2 people, 16.67%
Memory Loss: 2 people, 16.67%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 2 people, 16.67%
Incontinence (lack of moderation or self-control): 1 person, 8.33%

What are the existing conditions these people have? *

Weight Decreased: 9 people, 75.00%
High Blood Pressure: 5 people, 41.67%
High Blood Cholesterol: 2 people, 16.67%
Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 8.33%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Qsymia and have Poor quality sleep?

- Check whether Poor quality sleep is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Qsymia:

Qsymia (4,530 reports)

Poor quality sleep treatments and more:

Poor quality sleep (25,207 reports)

How severe was Poor quality sleep and when was it recovered:

Poor quality sleep in Qsymia

Expand to all the drugs that have ingredients of phentermine hydrochloride; topiramate:

Poor quality sleep and drugs with ingredients of phentermine hydrochloride; topiramate

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Qsymia:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Poor quality sleep:

Poor quality sleep (1,264 drugs)

Browse all the conditions that are associated with Poor quality sleep:

Poor quality sleep (1,163 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on phentermine hydrochloride; topiramate (the active ingredients of Qsymia) and Qsymia (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.