Quinine and Clostridium difficile colitis - a phase IV clinical study of FDA data

Summary:

Clostridium difficile colitis is reported as a side effect among people who take Quinine (cinchona), especially for people who are female, 60+ old, also take Prednisone, and have Multiple myeloma.

The phase IV clinical study analyzes which people have Clostridium difficile colitis when taking Quinine. It is created by eHealthMe based on reports of 4,887 people who have side effects when taking Quinine from the FDA, and is updated regularly.

What is Quinine?

Quinine has active ingredients of cinchona. It is often used in leg pain. eHealthMe is studying from 4,981 Quinine users. Check the latest studies of Quinine.

What is Clostridium difficile colitis?

Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection) is found to be associated with 1,042 drugs and 1,783 conditions by eHealthMe. Check the latest studies of Clostridium difficile colitis.

On Jul, 13, 2026

4,887 people reported to have side effects when taking Quinine.
Among them, 57 people (1.17%) have Clostridium difficile colitis.

Could Quinine cause Clostridium difficile colitis?

Among these 57 people:

What is the gender of people who have Clostridium difficile colitis when taking Quinine? *

female: 91.23 %
male: 8.77 %

What is the age of people who have Clostridium difficile colitis when taking Quinine? *

What are other drugs people take besides Quinine? *

What are other side effects people have besides Clostridium difficile colitis? *

Dyspnea (difficult or laboured breathing): 32 people, 56.14%
Neuropathy Peripheral (surface nerve damage): 32 people, 56.14%
Fall: 32 people, 56.14%
Chest Pain: 31 people, 54.39%
Cardiac Failure: 30 people, 52.63%
Haemorrhoids (a swollen vein or group of veins in the region of the anus): 30 people, 52.63%
Constipation: 30 people, 52.63%
Abdominal Pain Upper: 30 people, 52.63%
Pain In Extremity: 27 people, 47.37%
Hypoaesthesia (reduced sense of touch or sensation): 27 people, 47.37%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 44 people, 77.19%
Muscle Spasms (muscle contraction): 37 people, 64.91%
Blood Glucose Increased: 30 people, 52.63%
Diabetes: 30 people, 52.63%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 13 people, 22.81%
Metastases To Meninges (cancer spreads to meninges): 9 people, 15.79%
Pulmonary Embolism (blockage of the main artery of the lung): 7 people, 12.28%
Metastases To Bone (cancer spreads to bone): 7 people, 12.28%
Metastatic Malignant Melanoma (spreadable cancer tumour of melanine): 2 people, 3.51%
Type 2 Diabetes: 1 person, 1.75%

* Approximation only. Some reports may have incomplete information.

Do you take Quinine and have Clostridium difficile colitis?

- Check whether Clostridium difficile colitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Quinine:

Quinine (4,981 reports)

Browse all side effects of Quinine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Clostridium difficile colitis:

Clostridium difficile colitis (1,042 drugs)

Browse all the conditions that are associated with Clostridium difficile colitis:

Clostridium difficile colitis (1,783 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on cinchona (the active ingredients of Quinine) and Quinine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.