Qutenza and Application site reaction - a phase IV clinical study of FDA data

Summary:

Application site reaction is reported as a side effect among people who take Qutenza (capsaicin), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Neurontin, and have Neuralgia.

The phase IV clinical study analyzes which people have Application site reaction when taking Qutenza. It is created by eHealthMe based on reports of 882 people who have side effects when taking Qutenza from the FDA, and is updated regularly.

What is Qutenza?

Qutenza has active ingredients of capsaicin. eHealthMe is studying from 883 Qutenza users. Check the latest studies of Qutenza.

What is Application site reaction?

Application site reaction is found to be associated with 377 drugs and 550 conditions by eHealthMe. Check the latest studies of Application site reaction.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

882 people reported to have side effects when taking Qutenza.
Among them, 11 people (1.25%) have Application site reaction.

Could Qutenza cause Application site reaction?

Among these 11 people:

How long have people been on Qutenza when they have Application site reaction? *

What is the gender of people who have Application site reaction when taking Qutenza? *

female: 72.73 %
male: 27.27 %

What is the age of people who have Application site reaction when taking Qutenza? *

What are other drugs people take besides Qutenza? *

Neurontin: 2 people, 18.18%
Trileptal: 1 person, 9.09%
Paracetamol: 1 person, 9.09%
Morphine: 1 person, 9.09%

What are other side effects people have besides Application site reaction? *

Application Site Pain: 7 people, 63.64%
Application Site Papules (solid elevation of skin with no visible fluid at application site): 4 people, 36.36%
Presyncope: 2 people, 18.18%
Application Site Necrosis (death of body tissue at application site): 2 people, 18.18%
Drug Ineffective: 2 people, 18.18%
Application Site Pruritus (application site severe itching of the skin): 2 people, 18.18%
Burns Third Degree: 2 people, 18.18%
Burns Second Degree: 2 people, 18.18%
Application Site Rash: 2 people, 18.18%
Application Site Warmth: 2 people, 18.18%

What are the existing conditions these people have? *

Neuralgia (pain in one or more nerves): 5 people, 45.45%
Pain: 2 people, 18.18%
Urticaria Chronic (long lasting rash of round, red welts on the skin that itch intensely): 1 person, 9.09%
Post Herpetic Neuralgia (neuralgia caused by the varicella zoster virus): 1 person, 9.09%
Phantom Pain: 1 person, 9.09%
Complex Regional Pain Syndrome (long lasting pain condition most often affecting one of the limbs (arms, legs, hands, or feet)): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Qutenza and have Application site reaction?

- Check whether Application site reaction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Qutenza:

Qutenza (883 reports)

Browse all side effects of Qutenza:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Application site reaction:

Application site reaction (377 drugs)

Browse all the conditions that are associated with Application site reaction:

Application site reaction (550 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on capsaicin (the active ingredients of Qutenza) and Qutenza (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.