Rabeprazole sodium and Neuroleptic malignant syndrome - a phase IV clinical study of FDA data

Summary:

Neuroleptic malignant syndrome is reported as a side effect among people who take Rabeprazole sodium (rabeprazole sodium), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Sertraline Hydrochloride, and have Depression.

The phase IV clinical study analyzes which people have Neuroleptic malignant syndrome when taking Rabeprazole sodium. It is created by eHealthMe based on reports of 15,623 people who have side effects when taking Rabeprazole sodium from the FDA, and is updated regularly.

What is Rabeprazole sodium?

Rabeprazole sodium has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 15,786 Rabeprazole sodium users. Check the latest studies of Rabeprazole sodium.

What is Neuroleptic malignant syndrome?

Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents) is found to be associated with 551 drugs and 771 conditions by eHealthMe. Check the latest studies of Neuroleptic malignant syndrome.

On Jul, 05, 2026

15,623 people reported to have side effects when taking Rabeprazole sodium.
Among them, 24 people (0.15%) have Neuroleptic malignant syndrome.

Could Rabeprazole sodium cause Neuroleptic malignant syndrome?

Among these 24 people:

How long have people been on Rabeprazole sodium when they have Neuroleptic malignant syndrome? *

What is the gender of people who have Neuroleptic malignant syndrome when taking Rabeprazole sodium? *

female: 50 %
male: 50 %

What is the age of people who have Neuroleptic malignant syndrome when taking Rabeprazole sodium? *

What are other drugs people take besides Rabeprazole sodium? *

Sertraline Hydrochloride: 8 people, 33.33%
Zyprexa: 7 people, 29.17%
Valsartan: 7 people, 29.17%
Mesalamine: 7 people, 29.17%
Metoclopramide: 5 people, 20.83%
Celecoxib: 4 people, 16.67%
Folic Acid: 4 people, 16.67%
Seroquel: 4 people, 16.67%
Methotrexate: 4 people, 16.67%
Enbrel: 4 people, 16.67%

What are other side effects people have besides Neuroleptic malignant syndrome? *

Overdose: 7 people, 29.17%
Clostridium Difficile Colitis (inflammation of colon by clostridium difficile bacteria infection): 7 people, 29.17%
Metabolic Acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body): 7 people, 29.17%
Dehydration (dryness resulting from the removal of water): 6 people, 25.00%
Acute Kidney Failure: 6 people, 25.00%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 5 people, 20.83%
Telangiectasia (small dilated blood vessels near the surface of the skin): 5 people, 20.83%
Bundle Branch Block Left (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the left ventricle): 5 people, 20.83%
Haematocrit Decreased: 4 people, 16.67%
Haemoglobin Decreased: 4 people, 16.67%

What are the existing conditions these people have? *

Depression: 7 people, 29.17%
Impaired Gastric Emptying: 6 people, 25.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 16.67%
Parkinson's Disease: 3 people, 12.50%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 12.50%
Delusion (a false belief or opinion): 2 people, 8.33%
Arrhythmias (irregular heartbeat): 2 people, 8.33%
Osteoporosis (bones weak and more likely to break): 2 people, 8.33%
Hallucinations (sensations that appear real but are created by your mind): 2 people, 8.33%
Delirium (wild excitement): 2 people, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Rabeprazole sodium and have Neuroleptic malignant syndrome?

- Check whether Neuroleptic malignant syndrome is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rabeprazole sodium:

Rabeprazole sodium (15,786 reports)

Browse all side effects of Rabeprazole sodium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Neuroleptic malignant syndrome:

Neuroleptic malignant syndrome (551 drugs)

Browse all the conditions that are associated with Neuroleptic malignant syndrome:

Neuroleptic malignant syndrome (771 conditions)

Related publications that referenced our studies

Og?odek E, Szota A, Araszkiewicz A, "Olanzapine-induced neuroleptic malignant syndrome after 10 years of treatment", Aust NZJ Psychiatry, 2013 Oct .
Og?odek E, Szota A, Araszkiewicz A, "Olanzapine-induced neuroleptic malignant syndrome after 10 years of treatment", Aust NZJ Psychiatry, 2013 Oct .

How the study uses the data?

The study uses data from the FDA. It is based on rabeprazole sodium (the active ingredients of Rabeprazole sodium) and Rabeprazole sodium (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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