Rabeprazole and Aplastic anemia - a phase IV clinical study of FDA data

Summary:

Aplastic anemia is reported as a side effect among people who take Rabeprazole (rabeprazole sodium), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Itraconazole, and have Iron overload.

The phase IV clinical study analyzes which people have Aplastic anemia when taking Rabeprazole. It is created by eHealthMe based on reports of 31,196 people who have side effects when taking Rabeprazole from the FDA, and is updated regularly.

What is Rabeprazole?

Rabeprazole has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 31,689 Rabeprazole users. Check the latest studies of Rabeprazole.

What is Aplastic anemia?

Aplastic anemia is found to be associated with 620 drugs and 886 conditions by eHealthMe. Check the latest studies of Aplastic anemia.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

31,196 people reported to have side effects when taking Rabeprazole.
Among them, 19 people (0.06%) have Aplastic anemia.

Could Rabeprazole cause Aplastic anemia?

Among these 19 people:

How long have people been on Rabeprazole when they have Aplastic anemia? *

What is the gender of people who have Aplastic anemia when taking Rabeprazole? *

female: 47.06 %
male: 52.94 %

What is the age of people who have Aplastic anemia when taking Rabeprazole? *

What are other drugs people take besides Rabeprazole? *

Itraconazole: 9 people, 47.37%
Methylprednisolone Sodium Succinate: 8 people, 42.11%
Prednisolone: 7 people, 36.84%
Deferasirox: 6 people, 31.58%
Fluconazole: 6 people, 31.58%
Sulfamethoprim: 6 people, 31.58%
Entecavir: 5 people, 26.32%
Furosemide: 5 people, 26.32%
Dexchlorpheniramine Maleate: 5 people, 26.32%
Cefepime Hydrochloride: 4 people, 21.05%

What are other side effects people have besides Aplastic anemia? *

Cytomegalovirus Infection: 7 people, 36.84%
Abdominal Pain Upper: 5 people, 26.32%
Renal Impairment (severely reduced kidney function): 5 people, 26.32%
Arrhythmias (irregular heartbeat): 5 people, 26.32%
Fever: 5 people, 26.32%
Therapeutic Response Decreased (less preventive response): 5 people, 26.32%
Oedema Peripheral (superficial swelling): 4 people, 21.05%
Face Oedema (swelling of face): 4 people, 21.05%
Hypokalemia (low potassium): 4 people, 21.05%
Infection: 4 people, 21.05%

What are the existing conditions these people have? *

Iron Overload: 5 people, 26.32%
High Blood Pressure: 4 people, 21.05%
Renal Impairment (severely reduced kidney function): 2 people, 10.53%
Allergies: 2 people, 10.53%
Face Oedema (swelling of face): 2 people, 10.53%
Oedema Peripheral (superficial swelling): 2 people, 10.53%
Cytomegalovirus Infection: 2 people, 10.53%
Depression: 1 person, 5.26%
Febrile Neutropenia (fever with reduced white blood cells): 1 person, 5.26%
Fatigue (feeling of tiredness): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Rabeprazole and have Aplastic anemia?

- Check whether Aplastic anemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rabeprazole:

Rabeprazole (31,689 reports)

Aplastic anemia treatments and more:

Aplastic anemia (14,870 reports)

Browse all side effects of Rabeprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Aplastic anemia:

Aplastic anemia (620 drugs)

Browse all the conditions that are associated with Aplastic anemia:

Aplastic anemia (886 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on rabeprazole sodium (the active ingredients of Rabeprazole) and Rabeprazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.