Rabeprazole and Hyperthyroidism - a phase IV clinical study of FDA data

Summary:

Hyperthyroidism is reported as a side effect among people who take Rabeprazole (rabeprazole sodium), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Pantoprazole, and have Asthma.

The phase IV clinical study analyzes which people have Hyperthyroidism when taking Rabeprazole. It is created by eHealthMe based on reports of 31,196 people who have side effects when taking Rabeprazole from the FDA, and is updated regularly.

What is Rabeprazole?

Rabeprazole has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 31,689 Rabeprazole users. Check the latest studies of Rabeprazole.

What is Hyperthyroidism?

Hyperthyroidism (over activity of the thyroid gland) is found to be associated with 1,000 drugs and 1,436 conditions by eHealthMe. Check the latest studies of Hyperthyroidism.

On May, 07, 2026

31,196 people reported to have side effects when taking Rabeprazole.
Among them, 72 people (0.23%) have Hyperthyroidism.

Could Rabeprazole cause Hyperthyroidism?

Among these 72 people:

How long have people been on Rabeprazole when they have Hyperthyroidism? *

What is the gender of people who have Hyperthyroidism when taking Rabeprazole? *

female: 79.1 %
male: 20.9 %

What is the age of people who have Hyperthyroidism when taking Rabeprazole? *

What are other drugs people take besides Rabeprazole? *

What are other side effects people have besides Hyperthyroidism? *

High Blood Pressure: 43 people, 59.72%
Upper Respiratory Tract Infection: 41 people, 56.94%
The Flu (the flu is caused by an influenza virus): 38 people, 52.78%
Breath Sounds Abnormal: 38 people, 52.78%
Productive Cough: 38 people, 52.78%
Polymyalgia Rheumatica (pain in many muscles): 38 people, 52.78%
Pneumonia: 38 people, 52.78%
Pain In Extremity: 38 people, 52.78%
Osteoporosis (bones weak and more likely to break): 38 people, 52.78%
Multiple Allergies (allergy to multiple agents): 38 people, 52.78%

What are the existing conditions these people have? *

Asthma: 24 people, 33.33%
Metastatic Renal Cell Carcinoma (spreadable kidney cell tumour): 5 people, 6.94%
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 5 people, 6.94%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 5 people, 6.94%
Malignant Melanoma (skin cancer rises from melancytes): 4 people, 5.56%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 4.17%
Pancreatitis (inflammation of pancreas): 3 people, 4.17%
Immunodeficiency Common Variable: 3 people, 4.17%
Lung Adenocarcinoma Stage Ii (the cancer has spread to some lymph nodes near the original tumour): 3 people, 4.17%
Hepatic Neoplasm Malignant (liver cancer): 2 people, 2.78%

* Approximation only. Some reports may have incomplete information.

Do you take Rabeprazole and have Hyperthyroidism?

- Check whether Hyperthyroidism is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rabeprazole:

Rabeprazole (31,689 reports)

Hyperthyroidism treatments and more:

Hyperthyroidism (26,832 reports)

Browse all side effects of Rabeprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperthyroidism:

Hyperthyroidism (1,000 drugs)

Browse all the conditions that are associated with Hyperthyroidism:

Hyperthyroidism (1,436 conditions)

Related publications that referenced our studies

Dulani S, Dulani R, Lele S, Diagavane S, Anjankar S, Jaiswal N, Subramaniam PS, Juneja R, "Chronic Subdural Haematoma in a Case of Hyperthyroidism Presenting with Papilledema", Chinese Medicine, 2012 Dec .
Dulani S, Dulani R, Lele S, Diagavane S, Anjankar S, Jaiswal N, Subramaniam PS, Juneja R, "Chronic Subdural Haematoma in a Case of Hyperthyroidism Presenting with Papilledema", Chinese Medicine, 2012 Dec .

How the study uses the data?

The study uses data from the FDA. It is based on rabeprazole sodium (the active ingredients of Rabeprazole) and Rabeprazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.