Rabeprazole and Pathological fracture - a phase IV clinical study of FDA data

Summary:

Pathological fracture is reported as a side effect among people who take Rabeprazole (rabeprazole sodium), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Ramipril, and have Pain.

The phase IV clinical study analyzes which people have Pathological fracture when taking Rabeprazole. It is created by eHealthMe based on reports of 31,196 people who have side effects when taking Rabeprazole from the FDA, and is updated regularly.

What is Rabeprazole?

Rabeprazole has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 31,689 Rabeprazole users. Check the latest studies of Rabeprazole.

What is Pathological fracture?

Pathological fracture (broken bone caused by disease) is found to be associated with 837 drugs and 542 conditions by eHealthMe. Check the latest studies of Pathological fracture.



On Jul, 20, 2026

31,196 people reported to have side effects when taking Rabeprazole.
Among them, 29 people (0.09%) have Pathological fracture.

Could Rabeprazole cause Pathological fracture?

Among these 29 people:

How long have people been on Rabeprazole when they have Pathological fracture? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Pathological fracture when taking Rabeprazole? *

  • female: 53.85 %
  • male: 46.15 %

What is the age of people who have Pathological fracture when taking Rabeprazole? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 4.17 %
  • 50-59: 8.33 %
  • 60+: 87.5 %

What are other drugs people take besides Rabeprazole? *

  1. Zometa: 10 people, 34.48%
  2. Ramipril: 10 people, 34.48%
  3. Methylprednisolone: 9 people, 31.03%
  4. Gabapentin: 9 people, 31.03%
  5. Aredia: 9 people, 31.03%
  6. Morphine Sulfate: 8 people, 27.59%
  7. Dexamethasone: 8 people, 27.59%
  8. Sodium Bicarbonate: 8 people, 27.59%
  9. Ativan: 8 people, 27.59%
  10. Nystatin: 8 people, 27.59%

What are other side effects people have besides Pathological fracture? *

  1. Pain: 18 people, 62.07%
  2. Osteonecrosis Of Jaw (death of bone of jaw): 12 people, 41.38%
  3. Dyspnea (difficult or laboured breathing): 12 people, 41.38%
  4. Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 11 people, 37.93%
  5. Compression Fracture (fracture due to pressure caused by injury): 11 people, 37.93%
  6. Anaemia (lack of blood): 11 people, 37.93%
  7. Fatigue (feeling of tiredness): 10 people, 34.48%
  8. High Blood Pressure: 10 people, 34.48%
  9. Diarrhea: 10 people, 34.48%
  10. Jaw Fracture: 10 people, 34.48%

What are the existing conditions these people have? *

  1. Metastases To Bone (cancer spreads to bone): 9 people, 31.03%
  2. Pain: 9 people, 31.03%
  3. Insomnia (sleeplessness): 8 people, 27.59%
  4. Multiple Myeloma (cancer of the plasma cells): 8 people, 27.59%
  5. Hiccups (an involuntary spasm of the diaphragm and respiratory organs, with a sudden closure of the glottis and a sound like a cough): 7 people, 24.14%
  6. Stress And Anxiety: 7 people, 24.14%
  7. High Blood Pressure: 7 people, 24.14%
  8. Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 7 people, 24.14%
  9. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 6 people, 20.69%
  10. Osteoporosis (bones weak and more likely to break): 5 people, 17.24%

* Approximation only. Some reports may have incomplete information.

Do you take Rabeprazole and have Pathological fracture?

- Check whether Pathological fracture is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rabeprazole:

Pathological fracture treatments and more:

How severe was Pathological fracture and when was it recovered:

Expand to all the drugs that have ingredients of rabeprazole sodium:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Rabeprazole:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pathological fracture:

Browse all the conditions that are associated with Pathological fracture:


How the study uses the data?

The study uses data from the FDA. It is based on rabeprazole sodium (the active ingredients of Rabeprazole) and Rabeprazole (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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