Ranexa and Psoriasis - a phase IV clinical study of FDA data

Summary:

Psoriasis is reported as a side effect among people who take Ranexa (ranolazine), especially for people who are male, 60+ old, also take Humira, and have Psoriatic arthropathy.

The phase IV clinical study analyzes which people have Psoriasis when taking Ranexa. It is created by eHealthMe based on reports of 11,445 people who have side effects when taking Ranexa from the FDA, and is updated regularly.

What is Ranexa?

Ranexa has active ingredients of ranolazine. It is often used in angina. eHealthMe is studying from 11,758 Ranexa users. Check the latest studies of Ranexa.

What is Psoriasis?

Psoriasis (immune-mediated disease that affects the skin) is found to be associated with 1,489 drugs and 1,689 conditions by eHealthMe. Check the latest studies of Psoriasis.

On Feb, 22, 2026

11,445 people reported to have side effects when taking Ranexa.
Among them, 40 people (0.35%) have Psoriasis.

Among these 40 people:

What is the gender of people who have Psoriasis when taking Ranexa? *

female: 46.15 %
male: 53.85 %

What is the age of people who have Psoriasis when taking Ranexa? *

What are other drugs people take besides Ranexa? *

What are other side effects people have besides Psoriasis? *

Joint Pain: 6 people, 15.00%
Dyspnea (difficult or laboured breathing): 5 people, 12.50%
Coronary Artery Occlusion (complete obstruction of blood flow in a coronary artery): 4 people, 10.00%
Hypoaesthesia (reduced sense of touch or sensation): 4 people, 10.00%
Urinary Tract Infection: 4 people, 10.00%
Pain: 4 people, 10.00%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 4 people, 10.00%
Peripheral Swelling: 4 people, 10.00%
Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 4 people, 10.00%
Back Pain: 4 people, 10.00%

What are the existing conditions these people have? *

Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 15 people, 37.50%
High Blood Cholesterol: 7 people, 17.50%
High Blood Pressure: 7 people, 17.50%
Diabetes: 5 people, 12.50%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 5 people, 12.50%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 10.00%
Cardiac Disorder: 4 people, 10.00%
Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 10.00%
Depression: 4 people, 10.00%
Stress And Anxiety: 4 people, 10.00%

* Approximation only. Some reports may have incomplete information.

Do you take Ranexa and have Psoriasis?

- Check whether Psoriasis is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ranexa:

Ranexa (11,758 reports)

Psoriasis treatments and more:

Psoriasis (508,163 reports)

Browse all side effects of Ranexa:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Psoriasis:

Psoriasis (1,489 drugs)

Browse all the conditions that are associated with Psoriasis:

Psoriasis (1,689 conditions)

Related publications that referenced our studies

Mohagheghi MA, Omranipur R, Ensani F, Ghannadan A, Shahriaran S, Samiee F, Sedighi Z, "A Case of Advanced Unicentric Retroperitoneal Castleman's Disease, Associated With Psoriasis", Acta Medica Iranica, 2017 May .
Chiriac A, Brzezinski P, Stolnicu S, Podoleanu C, Moldovan C, Molnar C, Taranu T, "Eosinophilia–A rare possible adverse reaction during anti-tumor necrosis factor-alpha therapy for psoriasis", Journal of Dermatological Treatment, 2016 Mar .
Malisiewicz B, Murer C, Schmid JP, French LE, Schmid-Grendelmeier P, Navarini AA, "Eosinophilia during psoriasis treatment with TNF antagonists", Dermatology, 2013 Jan .
Mohagheghi MA, Omranipur R, Ensani F, Ghannadan A, Shahriaran S, Samiee F, Sedighi Z, "A Case of Advanced Unicentric Retroperitoneal Castleman's Disease, Associated With Psoriasis", Acta Medica Iranica, 2017 May .
Chiriac A, Brzezinski P, Stolnicu S, Podoleanu C, Moldovan C, Molnar C, Taranu T, "Eosinophilia–A rare possible adverse reaction during anti-tumor necrosis factor-alpha therapy for psoriasis", Journal of Dermatological Treatment, 2016 Mar .
Malisiewicz B, Murer C, Schmid JP, French LE, Schmid-Grendelmeier P, Navarini AA, "Eosinophilia during psoriasis treatment with TNF antagonists", Dermatology, 2013 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on ranolazine (the active ingredients of Ranexa) and Ranexa (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.