Ranitidine and Actinic cheilitis - a phase IV clinical study of FDA data

Summary:

Actinic cheilitis is reported as a side effect among people who take Ranitidine (ranitidine), especially for people who are male, 60+ old, also take Clopidogrel, and have Gout.

The phase IV clinical study analyzes which people have Actinic cheilitis when taking Ranitidine. It is created by eHealthMe based on reports of 233,168 people who have side effects when taking Ranitidine from the FDA, and is updated regularly.

What is Ranitidine?

Ranitidine has active ingredients of ranitidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 234,475 Ranitidine users. Check the latest studies of Ranitidine.

What is Actinic cheilitis?

Actinic cheilitis (inflammatory condition of the lips) is found to be associated with 4 drugs and 31 conditions by eHealthMe. Check the latest studies of Actinic cheilitis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

233,168 people reported to have side effects when taking Ranitidine.
Among them, 11 people (0.0%) have Actinic cheilitis.

Could Ranitidine cause Actinic cheilitis?

Among these 11 people:

What is the gender of people who have Actinic cheilitis when taking Ranitidine? *

female: 0.0 %
male: 100 %

What is the age of people who have Actinic cheilitis when taking Ranitidine? *

What are other drugs people take besides Ranitidine? *

Clopidogrel: 10 people, 90.91%
Humira: 1 person, 9.09%

What are other side effects people have besides Actinic cheilitis? *

Lip Pain: 10 people, 90.91%
Lip Disorder (disease of lip): 10 people, 90.91%
Hypoaesthesia Oral (reduced sense of touch or sensation in mouth): 10 people, 90.91%
Facial Paresis (weakness in facial muscle movement): 10 people, 90.91%
Facial Paralysis (loss of function of face muscle): 10 people, 90.91%
Dizziness: 10 people, 90.91%
Oral Herpes (viral infection of mouth): 9 people, 81.82%
Sleep Disorder: 1 person, 9.09%
Hepatic Function Abnormal: 1 person, 9.09%
Dermatitis Allergic (inflammation of the skin due allergic reaction): 1 person, 9.09%

What are the existing conditions these people have? *

Transient Ischaemic Attack (a transient episode of neurologic dysfunction caused by ischemia (loss of blood flow)): 10 people, 90.91%
High Blood Cholesterol: 10 people, 90.91%
Gout (uric acid crystals building up in the body): 10 people, 90.91%
Liver Disorder (liver diseases): 1 person, 9.09%
Insomnia (sleeplessness): 1 person, 9.09%
Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Ranitidine and have Actinic cheilitis?

- Check whether Actinic cheilitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ranitidine:

Ranitidine (234,475 reports)

Browse all side effects of Ranitidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Actinic cheilitis:

Actinic cheilitis (4 drugs)

Browse all the conditions that are associated with Actinic cheilitis:

Actinic cheilitis (31 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ranitidine (the active ingredients of Ranitidine) and Ranitidine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.