Ranitidine and Bipolar ii disorder - a phase IV clinical study of FDA data

Summary:

Bipolar ii disorder is reported as a side effect among people who take Ranitidine (ranitidine), especially for people who are female, 40-49 old, have been taking the drug for 6 - 12 months also take Seroquel, and have Narcolepsy.

The phase IV clinical study analyzes which people have Bipolar ii disorder when taking Ranitidine. It is created by eHealthMe based on reports of 233,168 people who have side effects when taking Ranitidine from the FDA, and is updated regularly.

What is Ranitidine?

Ranitidine has active ingredients of ranitidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 234,475 Ranitidine users. Check the latest studies of Ranitidine.

What is Bipolar ii disorder?

Bipolar ii disorder (characterized by at least one episode of hypomania and at least one episode of major depression) is found to be associated with 92 drugs and 360 conditions by eHealthMe. Check the latest studies of Bipolar ii disorder.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

233,168 people reported to have side effects when taking Ranitidine.
Among them, 11 people (0.0%) have Bipolar ii disorder.

Could Ranitidine cause Bipolar ii disorder?

Among these 11 people:

How long have people been on Ranitidine when they have Bipolar ii disorder? *

What is the gender of people who have Bipolar ii disorder when taking Ranitidine? *

female: 81.82 %
male: 18.18 %

What is the age of people who have Bipolar ii disorder when taking Ranitidine? *

What are other drugs people take besides Ranitidine? *

What are other side effects people have besides Bipolar ii disorder? *

Pain: 5 people, 45.45%
Stress And Anxiety: 5 people, 45.45%
General Physical Health Deterioration (weak health status): 4 people, 36.36%
Drug Ineffective: 4 people, 36.36%
Depression: 4 people, 36.36%
Suicidal Ideation: 4 people, 36.36%
Insomnia (sleeplessness): 4 people, 36.36%
Intervertebral Disc Protrusion (spinal disc protrusion): 3 people, 27.27%
Borderline Personality Disorder: 3 people, 27.27%
Nasopharyngitis (inflammation of the nasopharynx): 3 people, 27.27%

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 63.64%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 36.36%
Stress And Anxiety: 2 people, 18.18%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 9.09%
Sleep Disorder: 1 person, 9.09%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 1 person, 9.09%
Restless Leg Syndrome (a powerful urge to move your legs): 1 person, 9.09%
Multiple Allergies (allergy to multiple agents): 1 person, 9.09%
Insomnia (sleeplessness): 1 person, 9.09%
Ill-Defined Disorder: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Ranitidine and have Bipolar ii disorder?

- Check whether Bipolar ii disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ranitidine:

Ranitidine (234,475 reports)

Browse all side effects of Ranitidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Bipolar ii disorder:

Bipolar ii disorder (92 drugs)

Browse all the conditions that are associated with Bipolar ii disorder:

Bipolar ii disorder (360 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ranitidine (the active ingredients of Ranitidine) and Ranitidine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.