Ranitidine and Cardiotoxicity - a phase IV clinical study of FDA data

Summary:

Cardiotoxicity is reported as a side effect among people who take Ranitidine (ranitidine), especially for people who are male, 50-59 old, also take Ondansetron, and have Acute lymphocytic leukemia (all).

The phase IV clinical study analyzes which people have Cardiotoxicity when taking Ranitidine. It is created by eHealthMe based on reports of 233,168 people who have side effects when taking Ranitidine from the FDA, and is updated regularly.

What is Ranitidine?

Ranitidine has active ingredients of ranitidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 234,475 Ranitidine users. Check the latest studies of Ranitidine.

What is Cardiotoxicity?

Cardiotoxicity (damage to the heart muscle) is found to be associated with 384 drugs and 511 conditions by eHealthMe. Check the latest studies of Cardiotoxicity.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

233,168 people reported to have side effects when taking Ranitidine.
Among them, 22 people (0.01%) have Cardiotoxicity.

Among these 22 people:

What is the gender of people who have Cardiotoxicity when taking Ranitidine? *

female: 25 %
male: 75 %

What is the age of people who have Cardiotoxicity when taking Ranitidine? *

What are other drugs people take besides Ranitidine? *

Ondansetron: 10 people, 45.45%
Morphine: 6 people, 27.27%
Tamiflu: 4 people, 18.18%
Zoledronic Acid: 4 people, 18.18%
Acetylsalicylic Acid: 3 people, 13.64%
Clopidogrel: 3 people, 13.64%
Tradjenta: 2 people, 9.09%
Piperacillin And Tazobactam: 2 people, 9.09%
Vitamin D3: 2 people, 9.09%
Paclitaxel: 2 people, 9.09%

What are other side effects people have besides Cardiotoxicity? *

Nausea (feeling of having an urge to vomit): 2 people, 9.09%
Ventricular Extrasystoles (premature cardiac contraction): 2 people, 9.09%
Fatigue (feeling of tiredness): 2 people, 9.09%
Swallowing Difficulty: 2 people, 9.09%
Diarrhea: 2 people, 9.09%
Myopathy Toxic (a muscular disease in which the muscle fibres do not function due to toxin): 2 people, 9.09%
Cardiogenic Shock (inadequate circulation of blood): 2 people, 9.09%
Weight Decreased: 1 person, 4.55%
Disease Progression: 1 person, 4.55%
Constipation: 1 person, 4.55%

What are the existing conditions these people have? *

Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 4 people, 18.18%
Multiple Myeloma (cancer of the plasma cells): 2 people, 9.09%
Metastases To Bone (cancer spreads to bone): 2 people, 9.09%
Lung Squamous Cell Carcinoma Stage Iv (the lung cancer has spread to the other lung, and/or to lymph nodes, fluid around the lungs or heart, and/or other places in the body, such as the brain, liver, adrenal glands, kidneys, or bones): 2 people, 9.09%
Ewing's Sarcoma (malignant small, round, blue cell tumour): 2 people, 9.09%
Dyslipidaemia (abnormal amount of lipids): 2 people, 9.09%
Cutaneous Lupus Erythematosus (own immune system attacks various cells causing a wide variety of signs and symptoms): 2 people, 9.09%
Non-Small Cell Lung Cancer Stage Iiia: 1 person, 4.55%
Lymphocytic Infiltration (lymphocyte deposition): 1 person, 4.55%
Lung Cancer - Non-Small Cell (lung cancer): 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Ranitidine and have Cardiotoxicity?

- Check whether Cardiotoxicity is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ranitidine:

Ranitidine (234,475 reports)

Cardiotoxicity treatments and more:

Cardiotoxicity (8,120 reports)

Browse all side effects of Ranitidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Cardiotoxicity:

Cardiotoxicity (384 drugs)

Browse all the conditions that are associated with Cardiotoxicity:

Cardiotoxicity (511 conditions)

Related publications that referenced our studies

Alam, S., Illo, C., Ma, Y. T., & Punia, P. , "Gemcitabine-induced cardiotoxicity in patients receiving adjuvant chemotherapy for pancreatic cancer: a case series", Case reports in oncology, 2018 Jan .
Alam, S., Illo, C., Ma, Y. T., & Punia, P. , "Gemcitabine-induced cardiotoxicity in patients receiving adjuvant chemotherapy for pancreatic cancer: a case series", Case reports in oncology, 2018 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on ranitidine (the active ingredients of Ranitidine) and Ranitidine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.