Ranitidine and Hip joint replacement - a phase IV clinical study of FDA data

Summary:

Hip joint replacement is reported as a side effect among people who take Ranitidine (ranitidine), especially for people who are female, 60+ old, have been taking the drug for 2 - 5 years also take Prednisone, and have Rheumatoid arthritis.

The phase IV clinical study analyzes which people have Hip joint replacement when taking Ranitidine. It is created by eHealthMe based on reports of 233,168 people who have side effects when taking Ranitidine from the FDA, and is updated regularly.

What is Ranitidine?

Ranitidine has active ingredients of ranitidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 234,475 Ranitidine users. Check the latest studies of Ranitidine.

What is Hip joint replacement?

Hip joint replacement is found to be associated with 860 drugs and 1,062 conditions by eHealthMe. Check the latest studies of Hip joint replacement.



On Jul, 11, 2026

233,168 people reported to have side effects when taking Ranitidine.
Among them, 66 people (0.03%) have Hip joint replacement.

Could Ranitidine cause Hip joint replacement?

Among these 66 people:

How long have people been on Ranitidine when they have Hip joint replacement? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 25 %
  • 6 - 12 months: 25 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 50 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Hip joint replacement when taking Ranitidine? *

  • female: 68.18 %
  • male: 31.82 %

What is the age of people who have Hip joint replacement when taking Ranitidine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 1.85 %
  • 20-29: 5.56 %
  • 30-39: 3.7 %
  • 40-49: 18.52 %
  • 50-59: 31.48 %
  • 60+: 38.89 %

What are other drugs people take besides Ranitidine? *

  1. Prednisone: 20 people, 30.30%
  2. Humira: 15 people, 22.73%
  3. Methotrexate: 11 people, 16.67%
  4. Lorazepam: 10 people, 15.15%
  5. Folic Acid: 10 people, 15.15%
  6. Lisinopril: 10 people, 15.15%
  7. Magnesium: 10 people, 15.15%
  8. Acetaminophen: 10 people, 15.15%
  9. Coumadin: 9 people, 13.64%
  10. Heparin: 9 people, 13.64%

What are other side effects people have besides Hip joint replacement? *

  1. Weakness: 15 people, 22.73%
  2. Joint Pain: 14 people, 21.21%
  3. Aseptic Necrosis (the death of bone tissue due to a lack of blood supply): 14 people, 21.21%
  4. Pain: 13 people, 19.70%
  5. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 12 people, 18.18%
  6. Pneumonia: 10 people, 15.15%
  7. Itching: 10 people, 15.15%
  8. Nausea (feeling of having an urge to vomit): 9 people, 13.64%
  9. Fatigue (feeling of tiredness): 9 people, 13.64%
  10. Malaise (a feeling of general discomfort or uneasiness): 9 people, 13.64%

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 16 people, 24.24%
  2. Osteoporosis (bones weak and more likely to break): 9 people, 13.64%
  3. High Blood Pressure: 9 people, 13.64%
  4. Psoriasis (immune-mediated disease that affects the skin): 8 people, 12.12%
  5. Lambert-Eaton Syndrome (this means your immune system mistakenly targets healthy cells and tissues in the body): 6 people, 9.09%
  6. Hiv Infection: 6 people, 9.09%
  7. Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 6 people, 9.09%
  8. Pain: 5 people, 7.58%
  9. Bone Density Decreased: 5 people, 7.58%
  10. Depression: 5 people, 7.58%

* Approximation only. Some reports may have incomplete information.

Do you take Ranitidine and have Hip joint replacement?

- Check whether Hip joint replacement is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ranitidine:

Hip joint replacement treatments and more:

How severe was Hip joint replacement and when was it recovered:

Expand to all the drugs that have ingredients of ranitidine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ranitidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hip joint replacement:

Browse all the conditions that are associated with Hip joint replacement:


How the study uses the data?

The study uses data from the FDA. It is based on ranitidine (the active ingredients of Ranitidine) and Ranitidine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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