Ranitidine and Osteosclerosis - a phase IV clinical study of FDA data

Summary:

Osteosclerosis is reported as a side effect among people who take Ranitidine (ranitidine), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Zometa, and have Osteoporosis.

The phase IV clinical study analyzes which people have Osteosclerosis when taking Ranitidine. It is created by eHealthMe based on reports of 233,168 people who have side effects when taking Ranitidine from the FDA, and is updated regularly.

What is Ranitidine?

Ranitidine has active ingredients of ranitidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 234,475 Ranitidine users. Check the latest studies of Ranitidine.

What is Osteosclerosis?

Osteosclerosis (an elevation in bone density) is found to be associated with 638 drugs and 399 conditions by eHealthMe. Check the latest studies of Osteosclerosis.



On Aug, 08, 2026

233,168 people reported to have side effects when taking Ranitidine.
Among them, 61 people (0.03%) have Osteosclerosis.

Could Ranitidine cause Osteosclerosis?

Among these 61 people:

How long have people been on Ranitidine when they have Osteosclerosis? *

  • < 1 month: 25 %
  • 1 - 6 months: 50 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 25 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Osteosclerosis when taking Ranitidine? *

  • female: 46.3 %
  • male: 53.7 %

What is the age of people who have Osteosclerosis when taking Ranitidine? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 2.7 %
  • 20-29: 5.41 %
  • 30-39: 0.0 %
  • 40-49: 2.7 %
  • 50-59: 35.14 %
  • 60+: 54.05 %

What are other drugs people take besides Ranitidine? *

  1. Zometa: 43 people, 70.49%
  2. Dexamethasone: 27 people, 44.26%
  3. Celebrex: 26 people, 42.62%
  4. Aredia: 23 people, 37.70%
  5. Pepcid: 21 people, 34.43%
  6. Decadron: 21 people, 34.43%
  7. Aromasin: 20 people, 32.79%
  8. Coumadin: 18 people, 29.51%
  9. Metoclopramide: 17 people, 27.87%
  10. Acetaminophen: 17 people, 27.87%

What are other side effects people have besides Osteosclerosis? *

  1. Back Pain: 42 people, 68.85%
  2. Osteonecrosis Of Jaw (death of bone of jaw): 41 people, 67.21%
  3. Stress And Anxiety: 38 people, 62.30%
  4. Joint Pain: 35 people, 57.38%
  5. Osteoarthritis (a joint disease caused by cartilage loss in a joint): 34 people, 55.74%
  6. Pain: 33 people, 54.10%
  7. Diarrhea: 32 people, 52.46%
  8. Intervertebral Disc Degeneration (spinal disc degeneration): 31 people, 50.82%
  9. Rashes (redness): 30 people, 49.18%
  10. Spinal Osteoarthritis (joint cartilage loss in spine): 29 people, 47.54%

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 11 people, 18.03%
  2. Osteoporosis (bones weak and more likely to break): 11 people, 18.03%
  3. Pain: 9 people, 14.75%
  4. Metastases To Bone (cancer spreads to bone): 9 people, 14.75%
  5. Fibromyalgia (a long-term condition which causes pain all over the body): 6 people, 9.84%
  6. Bone Density Decreased: 6 people, 9.84%
  7. Drug Dependence: 5 people, 8.20%
  8. Bone Loss: 5 people, 8.20%
  9. Myosclerosis (hardening of muscle tissue): 4 people, 6.56%
  10. Stress And Anxiety: 4 people, 6.56%

* Approximation only. Some reports may have incomplete information.

Do you take Ranitidine and have Osteosclerosis?

- Check whether Osteosclerosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ranitidine:

Osteosclerosis treatments and more:

How severe was Osteosclerosis and when was it recovered:

Expand to all the drugs that have ingredients of ranitidine:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ranitidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Osteosclerosis:

Browse all the conditions that are associated with Osteosclerosis:


How the study uses the data?

The study uses data from the FDA. It is based on ranitidine (the active ingredients of Ranitidine) and Ranitidine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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