Ranitidine and Toxic encephalopathy - a phase IV clinical study of FDA data

Summary:

Toxic encephalopathy is reported as a side effect among people who take Ranitidine (ranitidine), especially for people who are female, 50-59 old, have been taking the drug for 6 - 12 months also take Lasix, and have Insomnia.

The phase IV clinical study analyzes which people have Toxic encephalopathy when taking Ranitidine. It is created by eHealthMe based on reports of 233,168 people who have side effects when taking Ranitidine from the FDA, and is updated regularly.

What is Ranitidine?

Ranitidine has active ingredients of ranitidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 234,475 Ranitidine users. Check the latest studies of Ranitidine.

What is Toxic encephalopathy?

Toxic encephalopathy (a degenerative neurologic disorder caused by exposure to toxic substances) is found to be associated with 423 drugs and 617 conditions by eHealthMe. Check the latest studies of Toxic encephalopathy.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 21, 2026

233,168 people reported to have side effects when taking Ranitidine.
Among them, 31 people (0.01%) have Toxic encephalopathy.

Could Ranitidine cause Toxic encephalopathy?

Among these 31 people:

How long have people been on Ranitidine when they have Toxic encephalopathy? *

What is the gender of people who have Toxic encephalopathy when taking Ranitidine? *

female: 61.29 %
male: 38.71 %

What is the age of people who have Toxic encephalopathy when taking Ranitidine? *

What are other drugs people take besides Ranitidine? *

What are other side effects people have besides Toxic encephalopathy? *

Confusional State: 11 people, 35.48%
Swallowing Difficulty: 8 people, 25.81%
Respiratory Distress (difficulty in breathing): 7 people, 22.58%
Fainting (loss of consciousness and postural tone): 7 people, 22.58%
Delirium (wild excitement): 6 people, 19.35%
Respiratory Acidosis (respiratory failure or ventilatory failure, causes the ph of blood and other bodily fluids to decrease): 6 people, 19.35%
Mental Status Changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation): 6 people, 19.35%
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 6 people, 19.35%
Septic Shock (shock due to blood infection): 6 people, 19.35%
Abdominal Pain: 6 people, 19.35%

What are the existing conditions these people have? *

Insomnia (sleeplessness): 9 people, 29.03%
Hepatitis C: 7 people, 22.58%
Pain: 6 people, 19.35%
Oedema Peripheral (superficial swelling): 5 people, 16.13%
Sinus Congestion (blockage of sinus): 4 people, 12.90%
Chronic Kidney Disease: 4 people, 12.90%
Deep Venous Thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis): 4 people, 12.90%
Depression: 4 people, 12.90%
Herpes Zoster: 4 people, 12.90%
Thrombosis (formation of a blood clot inside a blood vessel): 4 people, 12.90%

* Approximation only. Some reports may have incomplete information.

Do you take Ranitidine and have Toxic encephalopathy?

- Check whether Toxic encephalopathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ranitidine:

Ranitidine (234,475 reports)

Browse all side effects of Ranitidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Toxic encephalopathy:

Toxic encephalopathy (423 drugs)

Browse all the conditions that are associated with Toxic encephalopathy:

Toxic encephalopathy (617 conditions)

Related publications that referenced our studies

Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .
Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .

How the study uses the data?

The study uses data from the FDA. It is based on ranitidine (the active ingredients of Ranitidine) and Ranitidine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.