Ranolazine and Lactic acidosis - a phase IV clinical study of FDA data

Summary:

Lactic acidosis is reported as a side effect among people who take Ranolazine (ranolazine), especially for people who are male, 60+ old, also take Amlodipine, and have Type 2 diabetes.

The phase IV clinical study analyzes which people have Lactic acidosis when taking Ranolazine. It is created by eHealthMe based on reports of 9,903 people who have side effects when taking Ranolazine from the FDA, and is updated regularly.

What is Ranolazine?

Ranolazine has active ingredients of ranolazine. eHealthMe is studying from 9,939 Ranolazine users. Check the latest studies of Ranolazine.

What is Lactic acidosis?

Lactic acidosis (low ph in body tissues) is found to be associated with 995 drugs and 1,281 conditions by eHealthMe. Check the latest studies of Lactic acidosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

9,903 people reported to have side effects when taking Ranolazine.
Among them, 25 people (0.25%) have Lactic acidosis.

Among these 25 people:

What is the gender of people who have Lactic acidosis when taking Ranolazine? *

female: 8.7 %
male: 91.3 %

What is the age of people who have Lactic acidosis when taking Ranolazine? *

What are other drugs people take besides Ranolazine? *

What are other side effects people have besides Lactic acidosis? *

Dyspnea (difficult or laboured breathing): 20 people, 80.00%
General Physical Health Deterioration (weak health status): 19 people, 76.00%
Dizziness: 18 people, 72.00%
Fatigue (feeling of tiredness): 18 people, 72.00%
Hypoglycemia (low blood sugar): 18 people, 72.00%
Hypotension (abnormally low blood pressure): 4 people, 16.00%
Tachypnea: 3 people, 12.00%
Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions): 3 people, 12.00%
Bradycardia (abnormally slow heart action): 3 people, 12.00%
Confusional State: 3 people, 12.00%

What are the existing conditions these people have? *

Type 2 Diabetes: 21 people, 84.00%
High Blood Pressure: 18 people, 72.00%
High Blood Cholesterol: 18 people, 72.00%
Folate Deficiency (lack of folic acid): 18 people, 72.00%
Enlarged Prostate: 18 people, 72.00%
Coronary Heart Disease (narrowing or blockage of the coronary arteries): 18 people, 72.00%
Pain: 17 people, 68.00%
Hypokalemia (low potassium): 17 people, 68.00%
Arrhythmias (irregular heartbeat): 17 people, 68.00%
Prostate Cancer: 2 people, 8.00%

* Approximation only. Some reports may have incomplete information.

Do you take Ranolazine and have Lactic acidosis?

- Check whether Lactic acidosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ranolazine:

Ranolazine (9,939 reports)

Lactic acidosis treatments and more:

Lactic acidosis (34,314 reports)

Browse all side effects of Ranolazine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lactic acidosis:

Lactic acidosis (995 drugs)

Browse all the conditions that are associated with Lactic acidosis:

Lactic acidosis (1,281 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ranolazine (the active ingredients of Ranolazine) and Ranolazine (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.