Rapamune and Body temperature increased - a phase IV clinical study of FDA data

Summary:

Body temperature increased is reported as a side effect among people who take Rapamune (sirolimus), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Prograf, and have Chronic renal failure.

The phase IV clinical study analyzes which people have Body temperature increased when taking Rapamune. It is created by eHealthMe based on reports of 13,732 people who have side effects when taking Rapamune from the FDA, and is updated regularly.

What is Rapamune?

Rapamune has active ingredients of sirolimus. It is often used in kidney transplant. eHealthMe is studying from 13,848 Rapamune users. Check the latest studies of Rapamune.

What is Body temperature increased?

Body temperature increased is found to be associated with 1,351 drugs and 1,506 conditions by eHealthMe. Check the latest studies of Body temperature increased.



On Jul, 14, 2026

13,732 people reported to have side effects when taking Rapamune.
Among them, 48 people (0.35%) have Body temperature increased.

Could Rapamune cause Body temperature increased?

Among these 48 people:

How long have people been on Rapamune when they have Body temperature increased? *

  • < 1 month: 35 %
  • 1 - 6 months: 35 %
  • 6 - 12 months: 5 %
  • 1 - 2 years: 25 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Body temperature increased when taking Rapamune? *

  • female: 58.33 %
  • male: 41.67 %

What is the age of people who have Body temperature increased when taking Rapamune? *

  • 0-1: 0.0 %
  • 2-9: 6.25 %
  • 10-19: 4.17 %
  • 20-29: 10.42 %
  • 30-39: 14.58 %
  • 40-49: 12.5 %
  • 50-59: 14.58 %
  • 60+: 37.5 %

What are other drugs people take besides Rapamune? *

  1. Prograf: 10 people, 20.83%
  2. Cellcept: 9 people, 18.75%
  3. Prednisone: 9 people, 18.75%
  4. Bactrim: 7 people, 14.58%
  5. Norvasc: 7 people, 14.58%
  6. Aspirin: 7 people, 14.58%
  7. Lasix: 6 people, 12.50%
  8. Levothyroxine Sodium: 5 people, 10.42%
  9. Lipitor: 5 people, 10.42%
  10. Nystatin: 4 people, 8.33%

What are other side effects people have besides Body temperature increased? *

  1. Pleural Effusion (water on the lungs): 13 people, 27.08%
  2. Haemoglobin Decreased: 12 people, 25.00%
  3. Fever: 10 people, 20.83%
  4. Haematocrit Decreased: 9 people, 18.75%
  5. Fatigue (feeling of tiredness): 9 people, 18.75%
  6. Weight Decreased: 9 people, 18.75%
  7. Cough: 8 people, 16.67%
  8. Lymph Follicular Hypertrophy (an increase in the size of the lymph node follicles): 8 people, 16.67%
  9. Pericardial Effusion (fluid around the heart): 7 people, 14.58%
  10. Blood Glucose Increased: 7 people, 14.58%

What are the existing conditions these people have? *

  1. Hyperparathyroidism Secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary): 4 people, 8.33%
  2. Chronic Renal Failure (kidney failure): 4 people, 8.33%
  3. Upper Respiratory Tract Infection: 1 person, 2.08%
  4. Sepsis (a severe blood infection that can lead to organ failure and death): 1 person, 2.08%
  5. Metastases To Bone (cancer spreads to bone): 1 person, 2.08%
  6. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 1 person, 2.08%
  7. Fungal Infection: 1 person, 2.08%
  8. Chronic Granulomatous Disease (immune system cells are unable to kill some types of bacteria and fungi): 1 person, 2.08%
  9. Brain Neoplasm Benign (non-cancerous tumour of brain): 1 person, 2.08%
  10. Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 1 person, 2.08%

* Approximation only. Some reports may have incomplete information.

Do you take Rapamune and have Body temperature increased?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rapamune:

Body temperature increased treatments and more:

How severe was Body temperature increased and when was it recovered:

Expand to all the drugs that have ingredients of sirolimus:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Rapamune:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Body temperature increased:

Browse all the conditions that are associated with Body temperature increased:


How the study uses the data?

The study uses data from the FDA. It is based on sirolimus (the active ingredients of Rapamune) and Rapamune (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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