Rebif and Ear buzzing - a phase IV clinical study of FDA data
Summary:
Ear buzzing is reported as a side effect among people who take Rebif (interferon beta-1a), especially for people who are female, 40-49 old, have been taking the drug for 6 - 12 months also take Baclofen, and have Muscle spasms.
The phase IV clinical study analyzes which people have Ear buzzing when taking Rebif. It is created by eHealthMe based on reports of 60,837 people who have side effects when taking Rebif from the FDA, and is updated regularly.
What is Rebif?
Rebif has active ingredients of interferon beta-1a. It is often used in multiple sclerosis. eHealthMe is studying from 61,126 Rebif users. Check the latest studies of Rebif.
What is Ear buzzing?
Ear buzzing is found to be associated with 2,448 drugs and 3,076 conditions by eHealthMe. Check the latest studies of Ear buzzing.
60,837 people reported to have side effects when taking Rebif.
Among them, 121 people (0.2%) have Ear buzzing.

Among these 121 people:
How long have people been on Rebif when they have Ear buzzing? *
- < 1 month: 0.0 %
- 1 - 6 months: 15 %
- 6 - 12 months: 30 %
- 1 - 2 years: 10 %
- 2 - 5 years: 20 %
- 5 - 10 years: 25 %
- 10+ years: 0.0 %
What is the gender of people who have Ear buzzing when taking Rebif? *
- female: 84.17 %
- male: 15.83 %
What is the age of people who have Ear buzzing when taking Rebif? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 4.12 %
- 30-39: 16.49 %
- 40-49: 36.08 %
- 50-59: 32.99 %
- 60+: 10.31 %
What are other drugs people take besides Rebif? *
- Baclofen: 9 people, 7.44%
- Gabapentin: 8 people, 6.61%
- Ampyra: 8 people, 6.61%
- Xanax: 6 people, 4.96%
- Copaxone: 6 people, 4.96%
- Vitamin B12: 6 people, 4.96%
- Tecfidera: 6 people, 4.96%
- Tylenol: 6 people, 4.96%
- Lyrica: 5 people, 4.13%
- Tysabri: 5 people, 4.13%
What are other side effects people have besides Ear buzzing? *
- Headache (pain in head): 25 people, 20.66%
- Dizziness: 20 people, 16.53%
- Nausea (feeling of having an urge to vomit): 20 people, 16.53%
- Hypoaesthesia (reduced sense of touch or sensation): 20 people, 16.53%
- Fatigue (feeling of tiredness): 18 people, 14.88%
- Weakness: 17 people, 14.05%
- High Blood Pressure: 17 people, 14.05%
- Muscle Spasms (muscle contraction): 14 people, 11.57%
- Nausea And Vomiting: 14 people, 11.57%
- Pain: 13 people, 10.74%
What are the existing conditions these people have? *
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 5 people, 4.13%
- Muscle Spasms (muscle contraction): 5 people, 4.13%
- Depression: 3 people, 2.48%
- Type 2 Diabetes: 2 people, 1.65%
- Stress And Anxiety: 2 people, 1.65%
- Micturition Urgency (urgency to pass the urine): 2 people, 1.65%
- Gait Disturbance: 2 people, 1.65%
- High Blood Cholesterol: 2 people, 1.65%
- Headache (pain in head): 1 person, 0.83%
- Back Pain: 1 person, 0.83%
* Approximation only. Some reports may have incomplete information.
Do you take Rebif and have Ear buzzing?
- Check whether Ear buzzing is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Rebif:
- Rebif (61,126 reports)
Ear buzzing treatments and more:
- Ear buzzing (58,539 reports)
How severe was Ear buzzing and when was it recovered:
Expand to all the drugs that have ingredients of interferon beta-1a:
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Common Rebif side effects:
- Rebif side effect: Multiple sclerosis relapse (reoccurrence of a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath) (5,233 reports)
- Rebif side effect: Injection site erythema (redness at injection site) (4,097 reports)
- Rebif side effect: Influenza like illness (3,816 reports)
- Rebif side effect: Fall (3,681 reports)
- Rebif side effect: Injection site pain (3,313 reports)
Browse all side effects of Rebif:
a b c d e f g h i j k l m n o p q r s t u v w x y zCommon drugs associated with Ear buzzing:
- Aspirin side effect: Ear buzzing (2,601 reports)
- Cymbalta side effect: Ear buzzing (2,427 reports)
- Omeprazole side effect: Ear buzzing (1,980 reports)
- Prednisone side effect: Ear buzzing (1,929 reports)
- Gabapentin side effect: Ear buzzing (1,485 reports)
- Vitamin d side effect: Ear buzzing (1,427 reports)
- Simvastatin side effect: Ear buzzing (1,395 reports)
- Zide side effect: Ear buzzing (1,376 reports)
- Hydrochlorothiazide side effect: Ear buzzing (1,375 reports)
- Wellbutrin side effect: Ear buzzing (1,341 reports)
Browse all the drugs that are associated with Ear buzzing:
- Ear buzzing (2,448 drugs)
Common conditions associated with Ear buzzing:
- Depression aggravated: 3,635 reports
- Antidepressant therapy: 3,623 reports
- Hypertension: 2,663 reports
- Htn: 2,652 reports
- Arthritis - rheumatoid: 1,927 reports
- Anxiety: 1,913 reports
- Apprehension: 1,912 reports
- Pain exacerbated: 1,795 reports
- Pain relief: 1,778 reports
- Hypercholesterolaemia: 1,671 reports
Browse all the conditions that are associated with Ear buzzing:
- Ear buzzing (3,076 conditions)
Drugs similar to Rebif and Ear buzzing :
How the study uses the data?
The study uses data from the FDA. It is based on interferon beta-1a (the active ingredients of Rebif) and Rebif (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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