Rebif and Sciatica - a phase IV clinical study of FDA data

Summary:

Sciatica is reported as a side effect among people who take Rebif (interferon beta-1a), especially for people who are female, 50-59 old, have been taking the drug for 2 - 5 years also take Lexapro, and have Depression.

The phase IV clinical study analyzes which people have Sciatica when taking Rebif. It is created by eHealthMe based on reports of 60,837 people who have side effects when taking Rebif from the FDA, and is updated regularly.

What is Rebif?

Rebif has active ingredients of interferon beta-1a. It is often used in multiple sclerosis. eHealthMe is studying from 61,126 Rebif users. Check the latest studies of Rebif.

What is Sciatica?

Sciatica (a set of symptoms including pain caused by general compression or irritation of one of five spinal nerve roots of each sciatic nerve) is found to be associated with 1,146 drugs and 1,421 conditions by eHealthMe. Check the latest studies of Sciatica.

On Jan, 01, 2026

60,837 people reported to have side effects when taking Rebif.
Among them, 92 people (0.15%) have Sciatica.

Among these 92 people:

* Approximation only. Some reports may have incomplete information.

Do you take Rebif and have Sciatica?

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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Rebif:

Rebif (61,126 reports)

Sciatica treatments and more:

Sciatica (28,506 reports)

How severe was Sciatica and when was it recovered:

Sciatica in Rebif

Expand to all the drugs that have ingredients of interferon beta-1a:

Sciatica and drugs with ingredients of interferon beta-1a

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Common Rebif side effects:

Browse all side effects of Rebif:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Common drugs associated with Sciatica:

Browse all the drugs that are associated with Sciatica:

Sciatica (1,146 drugs)

Common conditions associated with Sciatica:

Rheumatoid arthritis: 3,984 reports
Osteoporosis: 1,578 reports
Psoriatic arthropathy aggravated: 1,283 reports
Pain: 1,076 reports
Pain relief: 1,069 reports
Ms: 1,038 reports
Hypertension: 930 reports
Htn: 922 reports
Hypercholesterolaemia: 804 reports
Psoriasis: 785 reports

Browse all the conditions that are associated with Sciatica:

Sciatica (1,421 conditions)

Drugs similar to Rebif and Sciatica :

How the study uses the data?

The study uses data from the FDA. It is based on interferon beta-1a (the active ingredients of Rebif) and Rebif (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.