Reclast and Ankylosing spondylitis - a phase IV clinical study of FDA data

Summary:

Ankylosing spondylitis is reported as a side effect among people who take Reclast (zoledronic acid), especially for people who are female, 60+ old, also take Pepcid, and have Asthma.

The phase IV clinical study analyzes which people have Ankylosing spondylitis when taking Reclast. It is created by eHealthMe based on reports of 15,446 people who have side effects when taking Reclast from the FDA, and is updated regularly.

What is Reclast?

Reclast has active ingredients of zoledronic acid. It is often used in osteoporosis. eHealthMe is studying from 15,774 Reclast users. Check the latest studies of Reclast.

What is Ankylosing spondylitis?

Ankylosing spondylitis (type of arthritis affecting the spine) is found to be associated with 746 drugs and 1,048 conditions by eHealthMe. Check the latest studies of Ankylosing spondylitis.

On Jul, 13, 2026

15,446 people reported to have side effects when taking Reclast.
Among them, 14 people (0.09%) have Ankylosing spondylitis.

Could Reclast cause Ankylosing spondylitis?

Among these 14 people:

What is the gender of people who have Ankylosing spondylitis when taking Reclast? *

female: 71.43 %
male: 28.57 %

What is the age of people who have Ankylosing spondylitis when taking Reclast? *

What are other drugs people take besides Reclast? *

What are other side effects people have besides Ankylosing spondylitis? *

Headache (pain in head): 5 people, 35.71%
Chills (felling of cold): 5 people, 35.71%
Pain: 5 people, 35.71%
Abdominal Discomfort: 4 people, 28.57%
Fever: 4 people, 28.57%
Nausea (feeling of having an urge to vomit): 4 people, 28.57%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 28.57%
Back Pain: 4 people, 28.57%
Dyspnea (difficult or laboured breathing): 4 people, 28.57%
Nausea And Vomiting: 4 people, 28.57%

What are the existing conditions these people have? *

High Blood Cholesterol: 3 people, 21.43%
Asthma: 3 people, 21.43%
Stress And Anxiety: 2 people, 14.29%
Sleep Disorder: 2 people, 14.29%
Cushing's Syndrome (obesity, a rounded face, increased fat): 2 people, 14.29%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 14.29%
Type 1 Diabetes: 1 person, 7.14%
Thyroid Diseases: 1 person, 7.14%
Spondyloarthropathy (any joint disease of the vertebral column): 1 person, 7.14%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Reclast and have Ankylosing spondylitis?

- Check whether Ankylosing spondylitis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Reclast:

Reclast (15,774 reports)

Browse all side effects of Reclast:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Ankylosing spondylitis:

Ankylosing spondylitis (746 drugs)

Browse all the conditions that are associated with Ankylosing spondylitis:

Ankylosing spondylitis (1,048 conditions)

Related publications that referenced our studies

Hung YM, Cheng CC, Wann SR, Lin SL, "Ankylosing spondylitis associated with pulmonary arterial hypertension", Internal Medicine, 2016 Jan .
Hung YM, Cheng CC, Wann SR, Lin SL, "Ankylosing spondylitis associated with pulmonary arterial hypertension", Internal Medicine, 2016 Jan .

How the study uses the data?

The study uses data from the FDA. It is based on zoledronic acid (the active ingredients of Reclast) and Reclast (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.