Reclast and Poor quality sleep - a phase IV clinical study of FDA data

Summary:

Poor quality sleep is reported as a side effect among people who take Reclast (zoledronic acid), especially for people who are female, 50-59 old, have been taking the drug for < 1 month also take Synthroid, and have Pain.

The phase IV clinical study analyzes which people have Poor quality sleep when taking Reclast. It is created by eHealthMe based on reports of 15,446 people who have side effects when taking Reclast from the FDA, and is updated regularly.

What is Reclast?

Reclast has active ingredients of zoledronic acid. It is often used in osteoporosis. eHealthMe is studying from 15,774 Reclast users. Check the latest studies of Reclast.

What is Poor quality sleep?

Poor quality sleep is found to be associated with 1,253 drugs and 1,167 conditions by eHealthMe. Check the latest studies of Poor quality sleep.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 03, 2026

15,446 people reported to have side effects when taking Reclast.
Among them, 17 people (0.11%) have Poor quality sleep.

Could Reclast cause Poor quality sleep?

Among these 17 people:

How long have people been on Reclast when they have Poor quality sleep? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Poor quality sleep when taking Reclast? *

  • female: 88.24 %
  • male: 11.76 %

What is the age of people who have Poor quality sleep when taking Reclast? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 7.14 %
  • 50-59: 50.0 %
  • 60+: 42.86 %

What are other drugs people take besides Reclast? *

  1. Synthroid: 7 people, 41.18%
  2. Ibuprofen: 5 people, 29.41%
  3. Acetaminophen: 3 people, 17.65%
  4. Calcium: 3 people, 17.65%
  5. Albuterol: 3 people, 17.65%
  6. Vitamin D: 3 people, 17.65%
  7. Atrovent: 3 people, 17.65%
  8. Zantac: 2 people, 11.76%
  9. Velcade: 2 people, 11.76%
  10. Valtrex: 2 people, 11.76%

What are other side effects people have besides Poor quality sleep? *

  1. Muscle Aches (muscle pain): 9 people, 52.94%
  2. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 9 people, 52.94%
  3. Headache (pain in head): 7 people, 41.18%
  4. Chest Pain: 7 people, 41.18%
  5. Muscle Spasms (muscle contraction): 6 people, 35.29%
  6. Chills (felling of cold): 6 people, 35.29%
  7. Pain: 6 people, 35.29%
  8. Feeling Abnormal: 5 people, 29.41%
  9. Neck Pain: 5 people, 29.41%
  10. Joint Pain: 4 people, 23.53%

What are the existing conditions these people have? *

  1. Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets): 2 people, 11.76%
  2. Pain: 2 people, 11.76%
  3. Sleep Phase Rhythm Disturbance (heart rate disturbances during sleep): 1 person, 5.88%
  4. Sexual Intercourse - Painful: 1 person, 5.88%
  5. Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose): 1 person, 5.88%
  6. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.88%
  7. Musculoskeletal Discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves): 1 person, 5.88%
  8. Insomnia (sleeplessness): 1 person, 5.88%
  9. Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 5.88%
  10. Asthma: 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Reclast and have Poor quality sleep?

- Check whether Poor quality sleep is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Reclast:

Poor quality sleep treatments and more:

How severe was Poor quality sleep and when was it recovered:

Expand to all the drugs that have ingredients of zoledronic acid:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Reclast:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Poor quality sleep:

Browse all the conditions that are associated with Poor quality sleep:


How the study uses the data?

The study uses data from the FDA. It is based on zoledronic acid (the active ingredients of Reclast) and Reclast (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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