Reglan and Formication - a phase IV clinical study of FDA data

Summary:

Formication is reported as a side effect among people who take Reglan (metoclopramide hydrochloride), especially for people who are female, 40-49 old, have been taking the drug for < 1 month also take Aspirin, and have Depression.

The phase IV clinical study analyzes which people have Formication when taking Reglan. It is created by eHealthMe based on reports of 28,854 people who have side effects when taking Reglan from the FDA, and is updated regularly.

What is Reglan?

Reglan has active ingredients of metoclopramide hydrochloride. It is often used in gastroparesis. eHealthMe is studying from 29,455 Reglan users. Check the latest studies of Reglan.

What is Formication?

Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin) is found to be associated with 564 drugs and 913 conditions by eHealthMe. Check the latest studies of Formication.

On Oct, 21, 2025

28,854 people reported to have side effects when taking Reglan.
Among them, 22 people (0.08%) have Formication.

Among these 22 people:

How long have people been on Reglan when they have Formication? *

What is the gender of people who have Formication when taking Reglan? *

female: 76.19 %
male: 23.81 %

What is the age of people who have Formication when taking Reglan? *

What are other drugs people take besides Reglan? *

What are other side effects people have besides Formication? *

Agitation (state of anxiety or nervous excitement): 7 people, 31.82%
Feeling Abnormal: 7 people, 31.82%
Stress And Anxiety: 7 people, 31.82%
Nausea And Vomiting: 6 people, 27.27%
Insomnia (sleeplessness): 6 people, 27.27%
Fatigue (feeling of tiredness): 5 people, 22.73%
Depression: 5 people, 22.73%
Weakness: 4 people, 18.18%
Tremor (trembling or shaking movements in one or more parts of your body): 4 people, 18.18%
Dyskinesia (abnormality or impairment of voluntary movement): 3 people, 13.64%

What are the existing conditions these people have? *

Stress And Anxiety: 2 people, 9.09%
Restless Leg Syndrome (a powerful urge to move your legs): 2 people, 9.09%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 9.09%
Depression: 2 people, 9.09%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 1 person, 4.55%
Diabetes: 1 person, 4.55%
Cancer Pain: 1 person, 4.55%
Cardiac Failure Congestive: 1 person, 4.55%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 1 person, 4.55%
Impaired Gastric Emptying: 1 person, 4.55%

* Approximation only. Some reports may have incomplete information.

Do you take Reglan and have Formication?

- Check whether Formication is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Reglan:

Reglan (29,455 reports)

Formication treatments and more:

Formication (8,246 reports)

Browse all side effects of Reglan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Formication:

Formication (564 drugs)

Browse all the conditions that are associated with Formication:

Formication (913 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metoclopramide hydrochloride (the active ingredients of Reglan) and Reglan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.