Reglan and Initial insomnia - a phase IV clinical study of FDA data

Summary:

Initial insomnia is reported as a side effect among people who take Reglan (metoclopramide hydrochloride), especially for people who are female, 50-59 old, also take Flexeril, and have Migraine.

The phase IV clinical study analyzes which people have Initial insomnia when taking Reglan. It is created by eHealthMe based on reports of 28,854 people who have side effects when taking Reglan from the FDA, and is updated regularly.

What is Reglan?

Reglan has active ingredients of metoclopramide hydrochloride. It is often used in gastroparesis. eHealthMe is studying from 29,455 Reglan users. Check the latest studies of Reglan.

What is Initial insomnia?

Initial insomnia (feeling of inadequate or poor-quality sleep) is found to be associated with 765 drugs and 682 conditions by eHealthMe. Check the latest studies of Initial insomnia.

On Feb, 07, 2026

28,854 people reported to have side effects when taking Reglan.
Among them, 14 people (0.05%) have Initial insomnia.

Among these 14 people:

What is the gender of people who have Initial insomnia when taking Reglan? *

female: 85.71 %
male: 14.29 %

What is the age of people who have Initial insomnia when taking Reglan? *

What are other drugs people take besides Reglan? *

What are other side effects people have besides Initial insomnia? *

Headache (pain in head): 6 people, 42.86%
Migraine (headache): 6 people, 42.86%
Weakness: 5 people, 35.71%
Fatigue (feeling of tiredness): 5 people, 35.71%
Nausea And Vomiting: 5 people, 35.71%
Fibromyalgia (a long-term condition which causes pain all over the body): 4 people, 28.57%
Back Pain: 4 people, 28.57%
Drug Ineffective: 4 people, 28.57%
Neck Pain: 4 people, 28.57%
Malaise (a feeling of general discomfort or uneasiness): 4 people, 28.57%

What are the existing conditions these people have? *

Migraine (headache): 5 people, 35.71%
Occipital Neuralgia (a condition characterized by chronic pain in the upper neck): 3 people, 21.43%
Nausea And Vomiting: 3 people, 21.43%
Headache (pain in head): 3 people, 21.43%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 21.43%
Ovarian Cancer (cancer of ovary): 2 people, 14.29%
Cerebral Disorder (brain disease): 2 people, 14.29%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 2 people, 14.29%
Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 1 person, 7.14%
Nervous System Disorder (a general class of medical conditions affecting the nervous system): 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

Do you take Reglan and have Initial insomnia?

- Check whether Initial insomnia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Reglan:

Reglan (29,455 reports)

Initial insomnia treatments and more:

Initial insomnia (12,139 reports)

Browse all side effects of Reglan:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Initial insomnia:

Initial insomnia (765 drugs)

Browse all the conditions that are associated with Initial insomnia:

Initial insomnia (682 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on metoclopramide hydrochloride (the active ingredients of Reglan) and Reglan (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.