Regranex and Joint swelling - a phase IV clinical study of FDA data

Summary:

Joint swelling is reported as a side effect among people who take Regranex (becaplermin), especially for people who are male, 60+ old, have been taking the drug for 1 - 6 months also take Oxycodone, and have Wound.

The phase IV clinical study analyzes which people have Joint swelling when taking Regranex. It is created by eHealthMe based on reports of 2,565 people who have side effects when taking Regranex from the FDA, and is updated regularly.

What is Regranex?

Regranex has active ingredients of becaplermin. eHealthMe is studying from 2,565 Regranex users. Check the latest studies of Regranex.

What is Joint swelling?

Joint swelling is found to be associated with 2,120 drugs and 2,938 conditions by eHealthMe. Check the latest studies of Joint swelling.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 01, 2026

2,565 people reported to have side effects when taking Regranex.
Among them, 11 people (0.43%) have Joint swelling.

Could Regranex cause Joint swelling?

Among these 11 people:

How long have people been on Regranex when they have Joint swelling? *

  • < 1 month: 25 %
  • 1 - 6 months: 75 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Joint swelling when taking Regranex? *

  • female: 27.27 %
  • male: 72.73 %

What is the age of people who have Joint swelling when taking Regranex? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 22.22 %
  • 50-59: 11.11 %
  • 60+: 66.67 %

What are other drugs people take besides Regranex? *

  1. Lantus: 2 people, 18.18%
  2. Asa: 2 people, 18.18%
  3. Metformin: 2 people, 18.18%
  4. Clopidogrel: 2 people, 18.18%
  5. Oxycodone: 2 people, 18.18%
  6. Cymbalta: 1 person, 9.09%
  7. Glyxambi: 1 person, 9.09%
  8. Gemzar: 1 person, 9.09%
  9. Femara: 1 person, 9.09%
  10. Faslodex: 1 person, 9.09%

What are other side effects people have besides Joint swelling? *

  1. Wound Complication: 3 people, 27.27%
  2. Pain In Extremity: 3 people, 27.27%
  3. Pain: 3 people, 27.27%
  4. Wound Infection: 2 people, 18.18%
  5. Actinic Keratosis (skin disease due to sun exposure): 1 person, 9.09%
  6. Hair Loss: 1 person, 9.09%
  7. Dyspnea (difficult or laboured breathing): 1 person, 9.09%
  8. Emotional Distress: 1 person, 9.09%
  9. Exostosis (formation of new bone on the surface of a bone): 1 person, 9.09%
  10. Fainting (loss of consciousness and postural tone): 1 person, 9.09%

What are the existing conditions these people have? *

  1. Wound: 6 people, 54.55%
  2. Diabetic Foot: 2 people, 18.18%
  3. Metastases To Bone (cancer spreads to bone): 1 person, 9.09%
  4. Diabetic Ulcer: 1 person, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Regranex and have Joint swelling?

- Check whether Joint swelling is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Regranex:

Joint swelling treatments and more:

How severe was Joint swelling and when was it recovered:

Expand to all the drugs that have ingredients of becaplermin:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Regranex:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Joint swelling:

Browse all the conditions that are associated with Joint swelling:


How the study uses the data?

The study uses data from the FDA. It is based on becaplermin (the active ingredients of Regranex) and Regranex (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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