Regular insulin and Atherosclerosis - a phase IV clinical study of FDA data

Summary:

Atherosclerosis is reported as a side effect among people who take Regular insulin (insulin pork), especially for people who are male, 60+ old, have been taking the drug for 10+ years also take Avandia, and have High blood pressure.

The phase IV clinical study analyzes which people have Atherosclerosis when taking Regular insulin. It is created by eHealthMe based on reports of 2,776 people who have side effects when taking Regular insulin from the FDA, and is updated regularly.

What is Regular insulin?

Regular insulin has active ingredients of insulin pork. It is often used in type 1 diabetes. eHealthMe is studying from 2,848 Regular insulin users. Check the latest studies of Regular insulin.

What is Atherosclerosis?

Atherosclerosis (disorder of the arteries) is found to be associated with 1,201 drugs and 1,533 conditions by eHealthMe. Check the latest studies of Atherosclerosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 31, 2026

2,776 people reported to have side effects when taking Regular insulin.
Among them, 12 people (0.43%) have Atherosclerosis.

Could Regular insulin cause Atherosclerosis?

Among these 12 people:

How long have people been on Regular insulin when they have Atherosclerosis? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 100 %

What is the gender of people who have Atherosclerosis when taking Regular insulin? *

  • female: 50 %
  • male: 50 %

What is the age of people who have Atherosclerosis when taking Regular insulin? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 44.44 %
  • 60+: 55.56 %

What are other drugs people take besides Regular insulin? *

  1. Amaryl: 4 people, 33.33%
  2. Atenolol: 4 people, 33.33%
  3. Avandia: 4 people, 33.33%
  4. Lactulose: 3 people, 25.00%
  5. Furosemide: 3 people, 25.00%
  6. Neurontin: 3 people, 25.00%
  7. Nitroglycerin: 3 people, 25.00%
  8. Levaquin: 3 people, 25.00%
  9. Paxil: 3 people, 25.00%
  10. Plavix: 3 people, 25.00%

What are other side effects people have besides Atherosclerosis? *

  1. Weakness: 4 people, 33.33%
  2. Cardiac Failure Congestive: 4 people, 33.33%
  3. Heart Attack: 4 people, 33.33%
  4. Fatigue (feeling of tiredness): 4 people, 33.33%
  5. White Blood Cell Count Decreased: 3 people, 25.00%
  6. Nausea (feeling of having an urge to vomit): 3 people, 25.00%
  7. Haemoglobin Decreased: 3 people, 25.00%
  8. Gynecomastia (enlargement of the gland tissue of the male breast): 2 people, 16.67%
  9. Orthopnea (shortness of breath (dyspnea) when lying down): 2 people, 16.67%
  10. Insomnia (sleeplessness): 2 people, 16.67%

What are the existing conditions these people have? *

  1. Type 2 Diabetes: 1 person, 8.33%
  2. High Blood Pressure: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Regular insulin and have Atherosclerosis?

- Check whether Atherosclerosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Regular insulin:

Atherosclerosis treatments and more:

How severe was Atherosclerosis and when was it recovered:

Expand to all the drugs that have ingredients of insulin pork:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Regular insulin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Atherosclerosis:

Browse all the conditions that are associated with Atherosclerosis:


How the study uses the data?

The study uses data from the FDA. It is based on insulin pork (the active ingredients of Regular insulin) and Regular insulin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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