Regular insulin and Necrosis - a phase IV clinical study of FDA data
Summary:
Necrosis is reported as a side effect among people who take Regular insulin (insulin pork), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Norvasc, and have Agitation.
The phase IV clinical study analyzes which people have Necrosis when taking Regular insulin. It is created by eHealthMe based on reports of 2,776 people who have side effects when taking Regular insulin from the FDA, and is updated regularly.
What is Regular insulin?
Regular insulin has active ingredients of insulin pork. It is often used in type 1 diabetes. eHealthMe is studying from 2,848 Regular insulin users. Check the latest studies of Regular insulin.
What is Necrosis?
Necrosis (the death of body tissue) is found to be associated with 750 drugs and 969 conditions by eHealthMe. Check the latest studies of Necrosis.
2,776 people reported to have side effects when taking Regular insulin.
Among them, 12 people (0.43%) have Necrosis.

Among these 12 people:
How long have people been on Regular insulin when they have Necrosis? *
- < 1 month: 100 %
- 1 - 6 months: 0.0 %
- 6 - 12 months: 0.0 %
- 1 - 2 years: 0.0 %
- 2 - 5 years: 0.0 %
- 5 - 10 years: 0.0 %
- 10+ years: 0.0 %
What is the gender of people who have Necrosis when taking Regular insulin? *
- female: 50 %
- male: 50 %
What is the age of people who have Necrosis when taking Regular insulin? *
- 0-1: 0.0 %
- 2-9: 0.0 %
- 10-19: 0.0 %
- 20-29: 0.0 %
- 30-39: 9.09 %
- 40-49: 27.27 %
- 50-59: 27.27 %
- 60+: 36.36 %
What are other drugs people take besides Regular insulin? *
- Rezulin: 3 people, 25.00%
- Glucotrol: 3 people, 25.00%
- Glucophage: 3 people, 25.00%
- Norvasc: 3 people, 25.00%
- Accupril: 2 people, 16.67%
- Ativan: 2 people, 16.67%
- Elavil: 2 people, 16.67%
- Pravachol: 2 people, 16.67%
- Dolobid: 1 person, 8.33%
- Imdur: 1 person, 8.33%
What are other side effects people have besides Necrosis? *
- Cellulitis (infection under the skin): 3 people, 25.00%
- Nausea (feeling of having an urge to vomit): 3 people, 25.00%
- Oedema Lower Limb (fluid collection in tissue of lower leg): 3 people, 25.00%
- Hypertension Aggravated (high blood pressure): 2 people, 16.67%
- Pulmonary Congestion (congestion in the lungs): 2 people, 16.67%
- Alanine Aminotransferase Increased: 2 people, 16.67%
- Aspartate Aminotransferase Increased: 2 people, 16.67%
- Blood Bilirubin Increased: 2 people, 16.67%
- Blood Lactate Dehydrogenase Increased: 2 people, 16.67%
- Cardiac Failure Congestive: 2 people, 16.67%
What are the existing conditions these people have? *
- Tachypnea: 1 person, 8.33%
- Nausea And Vomiting: 1 person, 8.33%
- Hypersensitivity: 1 person, 8.33%
- Hyperglycemia (high blood sugar): 1 person, 8.33%
- High Blood Pressure: 1 person, 8.33%
- Constipation: 1 person, 8.33%
- Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 8.33%
- Arrhythmias (irregular heartbeat): 1 person, 8.33%
- Agitation (state of anxiety or nervous excitement): 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Regular insulin and have Necrosis?
- Check whether Necrosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, long term effects of, and alternative drugs to Regular insulin:
- Regular insulin (2,848 reports)
Necrosis treatments and more:
- Necrosis (8,274 reports)
How severe was Necrosis and when was it recovered:
Expand to all the drugs that have ingredients of insulin pork:
- Necrosis and drugs with ingredients of insulin pork (33 reports)
Sub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Regular insulin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all the drugs that are associated with Necrosis:
- Necrosis (750 drugs)
Browse all the conditions that are associated with Necrosis:
- Necrosis (969 conditions)
How the study uses the data?
The study uses data from the FDA. It is based on insulin pork (the active ingredients of Regular insulin) and Regular insulin (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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