Relistor and Discomfort - a phase IV clinical study of FDA data

Summary:

Discomfort is reported as a side effect among people who take Relistor (methylnaltrexone bromide), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Oxycodone, and have Constipation.

The phase IV clinical study analyzes which people have Discomfort when taking Relistor. It is created by eHealthMe based on reports of 1,647 people who have side effects when taking Relistor from the FDA, and is updated regularly.

What is Relistor?

Relistor has active ingredients of methylnaltrexone bromide. eHealthMe is studying from 1,659 Relistor users. Check the latest studies of Relistor.

What is Discomfort?

Discomfort is found to be associated with 1,783 drugs and 1,566 conditions by eHealthMe. Check the latest studies of Discomfort.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 03, 2026

1,647 people reported to have side effects when taking Relistor.
Among them, 15 people (0.91%) have Discomfort.

Among these 15 people:

How long have people been on Relistor when they have Discomfort? *

What is the gender of people who have Discomfort when taking Relistor? *

female: 57.14 %
male: 42.86 %

What is the age of people who have Discomfort when taking Relistor? *

What are other drugs people take besides Relistor? *

What are other side effects people have besides Discomfort? *

Muscle Spasms (muscle contraction): 9 people, 60.00%
Pain: 7 people, 46.67%
Stress And Anxiety: 7 people, 46.67%
Feeling Abnormal: 5 people, 33.33%
Drug Ineffective: 5 people, 33.33%
Abdominal Pain: 5 people, 33.33%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 5 people, 33.33%
Sleep Apnea Syndrome: 5 people, 33.33%
Hyperhidrosis (abnormally increased sweating): 4 people, 26.67%
Back Pain: 4 people, 26.67%

What are the existing conditions these people have? *

Constipation: 7 people, 46.67%
Pain: 5 people, 33.33%
Muscle Spasticity (tight or stiff muscles and an inability to control those muscles): 2 people, 13.33%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 1 person, 6.67%
Cerebral Palsy: 1 person, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Relistor and have Discomfort?

- Check whether Discomfort is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Relistor:

Relistor (1,659 reports)

Discomfort treatments and more:

Discomfort (65,127 reports)

Browse all side effects of Relistor:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Discomfort:

Discomfort (1,783 drugs)

Browse all the conditions that are associated with Discomfort:

Discomfort (1,566 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on methylnaltrexone bromide (the active ingredients of Relistor) and Relistor (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.