Renagel and Hot flush - a phase IV clinical study of FDA data

Summary:

Hot flush is reported as a side effect among people who take Renagel (sevelamer hydrochloride), especially for people who are 60+ old, have been taking the drug for < 1 month also take Plavix, and have Herpes zoster.

The phase IV clinical study analyzes which people have Hot flush when taking Renagel. It is created by eHealthMe based on reports of 8,224 people who have side effects when taking Renagel from the FDA, and is updated regularly.

What is Renagel?

Renagel has active ingredients of sevelamer hydrochloride. eHealthMe is studying from 8,246 Renagel users. Check the latest studies of Renagel.

What is Hot flush?

Hot flush (sudden feelings of heat) is found to be associated with 1,769 drugs and 2,345 conditions by eHealthMe. Check the latest studies of Hot flush.



On Jul, 14, 2026

8,224 people reported to have side effects when taking Renagel.
Among them, 13 people (0.16%) have Hot flush.

Could Renagel cause Hot flush?

Among these 13 people:

How long have people been on Renagel when they have Hot flush? *

  • < 1 month: 100 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the age of people who have Hot flush when taking Renagel? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 41.67 %
  • 50-59: 8.33 %
  • 60+: 50.0 %

What are other drugs people take besides Renagel? *

  1. Plavix: 4 people, 30.77%
  2. Insulin: 3 people, 23.08%
  3. Xtandi: 3 people, 23.08%
  4. Zocor: 3 people, 23.08%
  5. Trental: 3 people, 23.08%
  6. Methotrexate: 3 people, 23.08%
  7. Celestone: 2 people, 15.38%
  8. Prelone: 2 people, 15.38%
  9. Prednisone: 2 people, 15.38%
  10. Folic Acid: 2 people, 15.38%

What are other side effects people have besides Hot flush? *

  1. Nausea (feeling of having an urge to vomit): 6 people, 46.15%
  2. Dizziness: 6 people, 46.15%
  3. Hypersensitivity: 5 people, 38.46%
  4. Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 5 people, 38.46%
  5. Diarrhea: 5 people, 38.46%
  6. Nausea And Vomiting: 4 people, 30.77%
  7. Pain: 4 people, 30.77%
  8. Fatigue (feeling of tiredness): 4 people, 30.77%
  9. Headache (pain in head): 3 people, 23.08%
  10. Gait Disturbance: 3 people, 23.08%

What are the existing conditions these people have? *

  1. Insomnia (sleeplessness): 2 people, 15.38%
  2. High Blood Pressure: 2 people, 15.38%
  3. Prostate Cancer: 2 people, 15.38%
  4. Pain: 2 people, 15.38%
  5. Oropharyngeal Pain: 2 people, 15.38%
  6. Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 2 people, 15.38%
  7. Herpes Zoster: 2 people, 15.38%
  8. Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 1 person, 7.69%
  9. Diabetic Gastroparesis (paralysis of the muscles of the stomach caused by diabetes): 1 person, 7.69%
  10. Fever: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Renagel and have Hot flush?

- Check whether Hot flush is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Renagel:

Hot flush treatments and more:

How severe was Hot flush and when was it recovered:

Expand to all the drugs that have ingredients of sevelamer hydrochloride:

Sub-studies by age:

0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Renagel:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hot flush:

Browse all the conditions that are associated with Hot flush:


How the study uses the data?

The study uses data from the FDA. It is based on sevelamer hydrochloride (the active ingredients of Renagel) and Renagel (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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