Repatha and Blood urea increased - a phase IV clinical study of FDA data

Summary:

Blood urea increased is reported as a side effect among people who take Repatha (evolocumab), especially for people who are female, 60+ old, have been taking the drug for 1 - 2 years also take Aspirin, and have Hyperlipidaemia.

The phase IV clinical study analyzes which people have Blood urea increased when taking Repatha. It is created by eHealthMe based on reports of 155,838 people who have side effects when taking Repatha from the FDA, and is updated regularly.

What is Repatha?

Repatha has active ingredients of evolocumab. It is often used in high blood cholesterol. eHealthMe is studying from 156,258 Repatha users. Check the latest studies of Repatha.

What is Blood urea increased?

Blood urea increased is found to be associated with 1,622 drugs and 1,992 conditions by eHealthMe. Check the latest studies of Blood urea increased.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 28, 2026

155,838 people reported to have side effects when taking Repatha.
Among them, 33 people (0.02%) have Blood urea increased.

Could Repatha cause Blood urea increased?

Among these 33 people:

How long have people been on Repatha when they have Blood urea increased? *

What is the gender of people who have Blood urea increased when taking Repatha? *

female: 60 %
male: 40 %

What is the age of people who have Blood urea increased when taking Repatha? *

What are other drugs people take besides Repatha? *

What are other side effects people have besides Blood urea increased? *

Blood Creatinine Increased: 18 people, 54.55%
Blood Glucose Increased: 11 people, 33.33%
Blood Creatine Increased: 5 people, 15.15%
Hypotension (abnormally low blood pressure): 5 people, 15.15%
Muscle Spasms (muscle contraction): 4 people, 12.12%
Fatigue (feeling of tiredness): 4 people, 12.12%
High Blood Pressure: 4 people, 12.12%
Hyperkalemia (damage to or disease of the kidney): 4 people, 12.12%
Renal Disorder (kidney disease): 3 people, 9.09%
Dehydration (dryness resulting from the removal of water): 3 people, 9.09%

What are the existing conditions these people have? *

Hyperlipidaemia (presence of excess lipids in the blood): 7 people, 21.21%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 5 people, 15.15%
Breast Cancer: 3 people, 9.09%
Carotid Artery Disease: 3 people, 9.09%
Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 3 people, 9.09%
Osteoporosis (bones weak and more likely to break): 3 people, 9.09%
Essential Hypertension (primary hypertension): 3 people, 9.09%
Diabetes: 3 people, 9.09%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 2 people, 6.06%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 2 people, 6.06%

* Approximation only. Some reports may have incomplete information.

Do you take Repatha and have Blood urea increased?

- Check whether Blood urea increased is associated with a drug or a condition
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Repatha:

Repatha (156,258 reports)

Browse all side effects of Repatha:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Blood urea increased:

Blood urea increased (1,622 drugs)

Browse all the conditions that are associated with Blood urea increased:

Blood urea increased (1,992 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on evolocumab (the active ingredients of Repatha) and Repatha (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.