Repatha and Diverticulum - a phase IV clinical study of FDA data

Summary:

Diverticulum is reported as a side effect among people who take Repatha (evolocumab), especially for people who are female, 60+ old, also take Allopurinol, and have Chronic kidney disease.

The phase IV clinical study analyzes which people have Diverticulum when taking Repatha. It is created by eHealthMe based on reports of 155,838 people who have side effects when taking Repatha from the FDA, and is updated regularly.

What is Repatha?

Repatha has active ingredients of evolocumab. It is often used in high blood cholesterol. eHealthMe is studying from 156,243 Repatha users. Check the latest studies of Repatha.

What is Diverticulum?

Diverticulum (out pouching of a hollow (or a fluid-filled) structure in the body) is found to be associated with 1,205 drugs and 980 conditions by eHealthMe. Check the latest studies of Diverticulum.

On Jan, 06, 2026

155,838 people reported to have side effects when taking Repatha.
Among them, 17 people (0.01%) have Diverticulum.

Among these 17 people:

What is the gender of people who have Diverticulum when taking Repatha? *

female: 81.25 %
male: 18.75 %

What is the age of people who have Diverticulum when taking Repatha? *

What are other drugs people take besides Repatha? *

What are other side effects people have besides Diverticulum? *

Fatigue (feeling of tiredness): 4 people, 23.53%
Back Pain: 4 people, 23.53%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 23.53%
Stress And Anxiety: 4 people, 23.53%
Headache (pain in head): 3 people, 17.65%
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall): 3 people, 17.65%
Dyspnea (difficult or laboured breathing): 3 people, 17.65%
Muscle Aches (muscle pain): 3 people, 17.65%
Injection Site Bruising: 2 people, 11.76%
Feeling Abnormal: 2 people, 11.76%

What are the existing conditions these people have? *

Iga Nephropathy (kidney disease- condition prevents the kidneys from filtering waste): 2 people, 11.76%
Chronic Kidney Disease: 2 people, 11.76%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.88%
Low Density Lipoprotein Increased (cholesterol increased in blood): 1 person, 5.88%
Hyperlipidaemia (presence of excess lipids in the blood): 1 person, 5.88%
Heart Disease: 1 person, 5.88%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.88%
Dyslipidaemia (abnormal amount of lipids): 1 person, 5.88%
Barrett's Oesophagus (barrett's oesophagus is a disorder in which the lining of the oesophagus (the tube that carries food from the throat to the stomach) is damaged by stomach acid and changed to a lining similar to that of the stomach): 1 person, 5.88%
Atherosclerosis (disorder of the arteries): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

Do you take Repatha and have Diverticulum?

- Check whether Diverticulum is associated with a drug or a condition (FREE)
- Predict drug outcomes for up to one year with AI (FREE)
- Get an AI agent to monitor your drugs continuously (FREE)

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Repatha:

Repatha (156,243 reports)

Diverticulum treatments and more:

Diverticulum (13,869 reports)

Browse all side effects of Repatha:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Diverticulum:

Diverticulum (1,205 drugs)

Browse all the conditions that are associated with Diverticulum:

Diverticulum (980 conditions)

Drugs similar to Repatha and Diverticulum :

How the study uses the data?

The study uses data from the FDA. It is based on evolocumab (the active ingredients of Repatha) and Repatha (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.