Repatha and Hyperlipidaemia - a phase IV clinical study of FDA data

Summary:

Hyperlipidaemia is reported as a side effect among people who take Repatha (evolocumab), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Aspirin, and have High blood pressure.

The phase IV clinical study analyzes which people have Hyperlipidaemia when taking Repatha. It is created by eHealthMe based on reports of 155,838 people who have side effects when taking Repatha from the FDA, and is updated regularly.

What is Repatha?

Repatha has active ingredients of evolocumab. It is often used in high blood cholesterol. eHealthMe is studying from 156,256 Repatha users. Check the latest studies of Repatha.

What is Hyperlipidaemia?

Hyperlipidaemia (presence of excess lipids in the blood) is found to be associated with 1,428 drugs and 1,407 conditions by eHealthMe. Check the latest studies of Hyperlipidaemia.

On Jul, 06, 2026

155,838 people reported to have side effects when taking Repatha.
Among them, 20 people (0.01%) have Hyperlipidaemia.

Among these 20 people:

How long have people been on Repatha when they have Hyperlipidaemia? *

What is the gender of people who have Hyperlipidaemia when taking Repatha? *

female: 55 %
male: 45 %

What is the age of people who have Hyperlipidaemia when taking Repatha? *

What are other drugs people take besides Repatha? *

What are other side effects people have besides Hyperlipidaemia? *

Abdominal Pain: 5 people, 25.00%
High Blood Pressure: 5 people, 25.00%
Nausea (feeling of having an urge to vomit): 4 people, 20.00%
Diarrhea: 4 people, 20.00%
Chest Pain: 3 people, 15.00%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 15.00%
Fatigue (feeling of tiredness): 3 people, 15.00%
Injection Site Pain: 3 people, 15.00%
Injection Site Mass: 2 people, 10.00%
Injection Site Inflammation: 2 people, 10.00%

What are the existing conditions these people have? *

High Blood Pressure: 3 people, 15.00%
Rickets (softening of bones): 2 people, 10.00%
Nephrotic Syndrome (kidney disease with proteinuria, hypoalbuminemia, and oedema): 2 people, 10.00%
Lipids Increased (excess lipid in body): 2 people, 10.00%
Haematuria (presence of blood in urine): 2 people, 10.00%
Type 2 Diabetes: 1 person, 5.00%
Percutaneous Coronary Intervention: 1 person, 5.00%
Low Density Lipoprotein Increased (cholesterol increased in blood): 1 person, 5.00%
Essential Hypertension (primary hypertension): 1 person, 5.00%
Diabetes: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

Do you take Repatha and have Hyperlipidaemia?

- Check whether Hyperlipidaemia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Repatha:

Repatha (156,256 reports)

Hyperlipidaemia treatments and more:

Hyperlipidaemia (86,394 reports)

Browse all side effects of Repatha:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Hyperlipidaemia:

Hyperlipidaemia (1,428 drugs)

Browse all the conditions that are associated with Hyperlipidaemia:

Hyperlipidaemia (1,407 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on evolocumab (the active ingredients of Repatha) and Repatha (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.