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Repatha and Lip blister - a phase IV clinical study of FDA data

Summary:

Lip blister is reported as a side effect among people who take Repatha (evolocumab), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Celexa, and have Hyperlipidaemia.

The phase IV clinical study analyzes which people have Lip blister when taking Repatha. It is created by eHealthMe based on reports of 155,838 people who have side effects when taking Repatha from the FDA, and is updated regularly.

What is Repatha?

Repatha has active ingredients of evolocumab. It is often used in high blood cholesterol. eHealthMe is studying from 156,256 Repatha users. Check the latest studies of Repatha.

What is Lip blister?

Lip blister is found to be associated with 354 drugs and 497 conditions by eHealthMe. Check the latest studies of Lip blister.

On Jul, 16, 2026

155,838 people reported to have side effects when taking Repatha.
Among them, 18 people (0.01%) have Lip blister.

Could Repatha cause Lip blister?

Among these 18 people:

How long have people been on Repatha when they have Lip blister? *

  • < 1 month: 50 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 50 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Lip blister when taking Repatha? *

  • female: 47.06 %
  • male: 52.94 %

What is the age of people who have Lip blister when taking Repatha? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 9.09 %
  • 60+: 90.91 %

What are other drugs people take besides Repatha? *

  1. Zofran: 1 person, 5.56%
  2. Xopenex Hfa: 1 person, 5.56%
  3. Theophylline: 1 person, 5.56%
  4. Singulair: 1 person, 5.56%
  5. Protonix: 1 person, 5.56%
  6. Promethazine Dm: 1 person, 5.56%
  7. Foradil: 1 person, 5.56%
  8. Flonase: 1 person, 5.56%
  9. Ezetimibe: 1 person, 5.56%
  10. Celexa: 1 person, 5.56%

What are other side effects people have besides Lip blister? *

  1. Lip Swelling: 4 people, 22.22%
  2. Tongue Blistering: 3 people, 16.67%
  3. Back Pain: 3 people, 16.67%
  4. Joint Pain: 3 people, 16.67%
  5. Rashes (redness): 2 people, 11.11%
  6. Chapped Lips (cracking, fissuring, and peeling of the skin f lip): 2 people, 11.11%
  7. Skin Exfoliation (removal of the oldest dead skin cells): 2 people, 11.11%
  8. Dyspnea (difficult or laboured breathing): 2 people, 11.11%
  9. Headache (pain in head): 1 person, 5.56%
  10. Lip Haemorrhage (bleeding lip): 1 person, 5.56%

What are the existing conditions these people have? *

  1. Hyperlipidaemia (presence of excess lipids in the blood): 3 people, 16.67%

* Approximation only. Some reports may have incomplete information.

Do you take Repatha and have Lip blister?

- Check whether Lip blister is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Repatha:

Lip blister treatments and more:

How severe was Lip blister and when was it recovered:

Expand to all the drugs that have ingredients of evolocumab:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Repatha:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Lip blister:

Browse all the conditions that are associated with Lip blister:

How the study uses the data?

The study uses data from the FDA. It is based on evolocumab (the active ingredients of Repatha) and Repatha (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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