Repatha and Pulmonary congestion - a phase IV clinical study of FDA data

Summary:

Pulmonary congestion is reported as a side effect among people who take Repatha (evolocumab), especially for people who are male, 60+ old, have been taking the drug for 6 - 12 months also take Nexium, and have Atrial fibrillation/flutter.

The phase IV clinical study analyzes which people have Pulmonary congestion when taking Repatha. It is created by eHealthMe based on reports of 155,838 people who have side effects when taking Repatha from the FDA, and is updated regularly.

What is Repatha?

Repatha has active ingredients of evolocumab. It is often used in high blood cholesterol. eHealthMe is studying from 156,256 Repatha users. Check the latest studies of Repatha.

What is Pulmonary congestion?

Pulmonary congestion (congestion in the lungs) is found to be associated with 1,275 drugs and 1,099 conditions by eHealthMe. Check the latest studies of Pulmonary congestion.

On Jul, 15, 2026

155,838 people reported to have side effects when taking Repatha.
Among them, 89 people (0.06%) have Pulmonary congestion.

Could Repatha cause Pulmonary congestion?

Among these 89 people:

How long have people been on Repatha when they have Pulmonary congestion? *

What is the gender of people who have Pulmonary congestion when taking Repatha? *

female: 32.56 %
male: 67.44 %

What is the age of people who have Pulmonary congestion when taking Repatha? *

What are other drugs people take besides Repatha? *

What are other side effects people have besides Pulmonary congestion? *

Dyspnea (difficult or laboured breathing): 35 people, 39.33%
Echocardiogram Abnormal: 29 people, 32.58%
Arrhythmias (irregular heartbeat): 28 people, 31.46%
Acute Coronary Syndrome (acute chest pain and other symptoms that happen because the heart does not get blood): 27 people, 30.34%
Breathing - Slowed Or Stopped: 27 people, 30.34%
Hyperkinesia (higher than normal levels of potassium in the circulating blood; associated with kidney failure or sometimes with the use of diuretic drugs): 27 people, 30.34%
Seizures (abnormal excessive or synchronous neuronal activity in the brain): 27 people, 30.34%
Loss Of Consciousness: 27 people, 30.34%
Hypokinesia (decreased bodily movement): 25 people, 28.09%
Ventricular Hypokinesia (muscle of one's heart does not contract as much as most peoples' hearts do): 25 people, 28.09%

What are the existing conditions these people have? *

Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 27 people, 30.34%
Stroke (sudden death of a portion of the brain cells due to a lack of oxygen): 21 people, 23.60%
Hyperlipidaemia (presence of excess lipids in the blood): 7 people, 7.87%
Low Density Lipoprotein Increased (cholesterol increased in blood): 4 people, 4.49%
High Density Lipoprotein Decreased: 2 people, 2.25%
Heart Disease: 2 people, 2.25%
Arteriosclerosis Coronary Artery (thickening and hardening of arteries- coronary artery): 2 people, 2.25%
Type 2 Diabetes: 1 person, 1.12%
Stress And Anxiety: 1 person, 1.12%
Pain: 1 person, 1.12%

* Approximation only. Some reports may have incomplete information.

Do you take Repatha and have Pulmonary congestion?

- Check whether Pulmonary congestion is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Repatha:

Repatha (156,256 reports)

Browse all side effects of Repatha:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Pulmonary congestion:

Pulmonary congestion (1,275 drugs)

Browse all the conditions that are associated with Pulmonary congestion:

Pulmonary congestion (1,099 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on evolocumab (the active ingredients of Repatha) and Repatha (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.