Requip xl and Heart attack - a phase IV clinical study of FDA data

Summary:

Heart attack is reported as a side effect among people who take Requip xl (ropinirole hydrochloride), especially for people who are male, 60+ old, have been taking the drug for < 1 month also take Requip, and have Asthma.

The phase IV clinical study analyzes which people have Heart attack when taking Requip xl. It is created by eHealthMe based on reports of 1,139 people who have side effects when taking Requip xl from the FDA, and is updated regularly.

What is Requip xl?

Requip xl has active ingredients of ropinirole hydrochloride. It is often used in parkinson's disease. eHealthMe is studying from 1,297 Requip xl users. Check the latest studies of Requip xl.

What is Heart attack?

Heart attack is found to be associated with 2,485 drugs and 3,296 conditions by eHealthMe. Check the latest studies of Heart attack.



On Jul, 06, 2026

1,139 people reported to have side effects when taking Requip xl.
Among them, 12 people (1.05%) have Heart attack.

Could Requip xl cause Heart attack?

Among these 12 people:

How long have people been on Requip xl when they have Heart attack? *

  • < 1 month: 50 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 50 %
  • 1 - 2 years: 0.0 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Heart attack when taking Requip xl? *

  • female: 41.67 %
  • male: 58.33 %

What is the age of people who have Heart attack when taking Requip xl? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 0.0 %
  • 60+: 100 %

What are other drugs people take besides Requip xl? *

  1. Stalevo 100: 5 people, 41.67%
  2. Requip: 5 people, 41.67%
  3. Amlodipine: 2 people, 16.67%
  4. Apomorphine Hydrochloride: 2 people, 16.67%
  5. Sinemet: 2 people, 16.67%
  6. Zoloft: 1 person, 8.33%
  7. Hydrocodone: 1 person, 8.33%
  8. Atenolol: 1 person, 8.33%
  9. Avandia: 1 person, 8.33%
  10. Azilect: 1 person, 8.33%

What are other side effects people have besides Heart attack? *

  1. Pneumonia: 3 people, 25.00%
  2. Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 25.00%
  3. Overdose: 2 people, 16.67%
  4. Weakness: 2 people, 16.67%
  5. Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 2 people, 16.67%
  6. Monoplegia (a paralysis of a single limb): 2 people, 16.67%
  7. Gallbladder Disorder: 2 people, 16.67%
  8. Cuts And Puncture Wounds: 2 people, 16.67%
  9. Neck Pain: 2 people, 16.67%
  10. Movement Disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness): 2 people, 16.67%

What are the existing conditions these people have? *

  1. Diabetes: 1 person, 8.33%
  2. Asthma: 1 person, 8.33%

* Approximation only. Some reports may have incomplete information.

Do you take Requip xl and have Heart attack?

- Check whether Heart attack is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Requip xl:

Heart attack treatments and more:

How severe was Heart attack and when was it recovered:

Expand to all the drugs that have ingredients of ropinirole hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Requip xl:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Heart attack:

Browse all the conditions that are associated with Heart attack:


How the study uses the data?

The study uses data from the FDA. It is based on ropinirole hydrochloride (the active ingredients of Requip xl) and Requip xl (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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