Requip and Common peroneal nerve dysfunction - a phase IV clinical study of FDA data

Summary:

Common peroneal nerve dysfunction is reported as a side effect among people who take Requip (ropinirole hydrochloride), especially for people who are male, 60+ old, have been taking the drug for 1 - 2 years also take Neurontin, and have Arthritis.

The phase IV clinical study analyzes which people have Common peroneal nerve dysfunction when taking Requip. It is created by eHealthMe based on reports of 21,866 people who have side effects when taking Requip from the FDA, and is updated regularly.

What is Requip?

Requip has active ingredients of ropinirole hydrochloride. It is often used in restless leg syndrome. eHealthMe is studying from 22,950 Requip users. Check the latest studies of Requip.

What is Common peroneal nerve dysfunction?

Common peroneal nerve dysfunction (dysfunction of nerve controlling movement and sensation to the lower leg, foot and toes) is found to be associated with 651 drugs and 1,129 conditions by eHealthMe. Check the latest studies of Common peroneal nerve dysfunction.



On Jul, 23, 2026

21,866 people reported to have side effects when taking Requip.
Among them, 15 people (0.07%) have Common peroneal nerve dysfunction.

Could Requip cause Common peroneal nerve dysfunction?

Among these 15 people:

How long have people been on Requip when they have Common peroneal nerve dysfunction? *

  • < 1 month: 0.0 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 100 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Common peroneal nerve dysfunction when taking Requip? *

  • female: 40 %
  • male: 60 %

What is the age of people who have Common peroneal nerve dysfunction when taking Requip? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 0.0 %
  • 30-39: 7.69 %
  • 40-49: 0.0 %
  • 50-59: 30.77 %
  • 60+: 61.54 %

What are other drugs people take besides Requip? *

  1. Cozaar: 5 people, 33.33%
  2. Lipitor: 5 people, 33.33%
  3. Neurontin: 5 people, 33.33%
  4. Folic Acid: 4 people, 26.67%
  5. Adderall 10: 4 people, 26.67%
  6. Seroquel: 4 people, 26.67%
  7. Gabapentin: 4 people, 26.67%
  8. Lutein: 3 people, 20.00%
  9. Losartan Potassium: 3 people, 20.00%
  10. Lithium Carbonate: 3 people, 20.00%

What are other side effects people have besides Common peroneal nerve dysfunction? *

  1. Fall: 8 people, 53.33%
  2. Neuropathy Peripheral (surface nerve damage): 7 people, 46.67%
  3. Fatigue (feeling of tiredness): 7 people, 46.67%
  4. Insomnia (sleeplessness): 7 people, 46.67%
  5. Muscle Spasms (muscle contraction): 7 people, 46.67%
  6. Stress And Anxiety: 7 people, 46.67%
  7. Depression: 6 people, 40.00%
  8. Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 6 people, 40.00%
  9. Muscle Atrophy (a decrease in the mass of the muscle): 6 people, 40.00%
  10. Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 6 people, 40.00%

What are the existing conditions these people have? *

  1. Sleep Disorder: 3 people, 20.00%
  2. High Blood Cholesterol: 3 people, 20.00%
  3. Depression: 3 people, 20.00%
  4. Dermatitis Herpetiformis (chronic blistering skin condition, characterized by blisters filled with a watery fluid): 3 people, 20.00%
  5. Gastrointestinal Motility Disorder (abnormal intestinal contractions): 3 people, 20.00%
  6. Sinus Disorder (disease of sinus): 3 people, 20.00%
  7. Hiatal Hernia (hernia resulting from the protrusion of part of the stomach through the diaphragm): 3 people, 20.00%
  8. Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 3 people, 20.00%
  9. Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 20.00%
  10. Depressed Mood: 2 people, 13.33%

* Approximation only. Some reports may have incomplete information.

Do you take Requip and have Common peroneal nerve dysfunction?

- Check whether Common peroneal nerve dysfunction is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Requip:

Common peroneal nerve dysfunction treatments and more:

How severe was Common peroneal nerve dysfunction and when was it recovered:

Expand to all the drugs that have ingredients of ropinirole hydrochloride:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Requip:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Common peroneal nerve dysfunction:

Browse all the conditions that are associated with Common peroneal nerve dysfunction:


How the study uses the data?

The study uses data from the FDA. It is based on ropinirole hydrochloride (the active ingredients of Requip) and Requip (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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