Requip and Endometriosis - a phase IV clinical study of FDA data

Summary:

Endometriosis is reported as a side effect among people who take Requip (ropinirole hydrochloride), especially for people who are 40-49 old, have been taking the drug for 1 - 6 months also take Dilaudid, and have Pain.

The phase IV clinical study analyzes which people have Endometriosis when taking Requip. It is created by eHealthMe based on reports of 21,866 people who have side effects when taking Requip from the FDA, and is updated regularly.

What is Requip?

Requip has active ingredients of ropinirole hydrochloride. It is often used in restless leg syndrome. eHealthMe is studying from 22,950 Requip users. Check the latest studies of Requip.

What is Endometriosis?

Endometriosis (appearance of endometrial tissue outside the uterus and causing pelvic pain) is found to be associated with 420 drugs and 562 conditions by eHealthMe. Check the latest studies of Endometriosis.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

21,866 people reported to have side effects when taking Requip.
Among them, 11 people (0.05%) have Endometriosis.

Among these 11 people:

How long have people been on Requip when they have Endometriosis? *

What is the age of people who have Endometriosis when taking Requip? *

What are other drugs people take besides Requip? *

What are other side effects people have besides Endometriosis? *

Dizziness: 7 people, 63.64%
Pain: 6 people, 54.55%
Dyspnea (difficult or laboured breathing): 5 people, 45.45%
Malabsorption (a state arising from abnormality in absorption of food nutrients across the gastrointestinal (gi) tract): 5 people, 45.45%
Back Pain: 4 people, 36.36%
Small Intestinal Obstruction (blockage in small intestine): 4 people, 36.36%
Internal Hernia (protrusion of an intraperitoneal viscous into a compartment or under a constricting band within the abdominal cavity): 4 people, 36.36%
Weight Increased: 4 people, 36.36%
Nausea (feeling of having an urge to vomit): 4 people, 36.36%
Nausea And Vomiting: 4 people, 36.36%

What are the existing conditions these people have? *

Pain: 7 people, 63.64%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 27.27%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 27.27%
Vitamin D Decreased: 2 people, 18.18%
Gastrointestinal Pain: 2 people, 18.18%
Back Pain: 2 people, 18.18%
Constipation: 2 people, 18.18%
Dehydration (dryness resulting from the removal of water): 2 people, 18.18%
Flank Pain (a distressing sensation experienced around the lower back and the upper abdomen): 2 people, 18.18%
Stress And Anxiety: 2 people, 18.18%

* Approximation only. Some reports may have incomplete information.

Do you take Requip and have Endometriosis?

- Check whether Endometriosis is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Requip:

Requip (22,950 reports)

Endometriosis treatments and more:

Endometriosis (19,678 reports)

Browse all side effects of Requip:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Endometriosis:

Endometriosis (420 drugs)

Browse all the conditions that are associated with Endometriosis:

Endometriosis (562 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ropinirole hydrochloride (the active ingredients of Requip) and Requip (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.