Requip and Muscle twitching - a phase IV clinical study of FDA data

Summary:

Muscle twitching is reported as a side effect among people who take Requip (ropinirole hydrochloride), especially for people who are female, 60+ old, have been taking the drug for < 1 month also take Seroquel, and have Depression.

The phase IV clinical study analyzes which people have Muscle twitching when taking Requip. It is created by eHealthMe based on reports of 21,866 people who have side effects when taking Requip from the FDA, and is updated regularly.

What is Requip?

Requip has active ingredients of ropinirole hydrochloride. It is often used in restless leg syndrome. eHealthMe is studying from 22,950 Requip users. Check the latest studies of Requip.

What is Muscle twitching?

Muscle twitching is found to be associated with 1,238 drugs and 1,905 conditions by eHealthMe. Check the latest studies of Muscle twitching.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 27, 2026

21,866 people reported to have side effects when taking Requip.
Among them, 83 people (0.38%) have Muscle twitching.

Among these 83 people:

How long have people been on Requip when they have Muscle twitching? *

What is the gender of people who have Muscle twitching when taking Requip? *

female: 70.51 %
male: 29.49 %

What is the age of people who have Muscle twitching when taking Requip? *

What are other drugs people take besides Requip? *

What are other side effects people have besides Muscle twitching? *

Dyskinesia (abnormality or impairment of voluntary movement): 23 people, 27.71%
Insomnia (sleeplessness): 22 people, 26.51%
Tremor (trembling or shaking movements in one or more parts of your body): 20 people, 24.10%
Nausea (feeling of having an urge to vomit): 19 people, 22.89%
Stress And Anxiety: 15 people, 18.07%
Dizziness: 15 people, 18.07%
Muscle Spasms (muscle contraction): 14 people, 16.87%
Fatigue (feeling of tiredness): 14 people, 16.87%
Pain In Extremity: 13 people, 15.66%
Feeling Abnormal: 12 people, 14.46%

What are the existing conditions these people have? *

Sleep Disorder: 9 people, 10.84%
Depression: 9 people, 10.84%
Pain: 8 people, 9.64%
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect): 4 people, 4.82%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 4.82%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 4.82%
Muscle Spasms (muscle contraction): 4 people, 4.82%
High Blood Cholesterol: 4 people, 4.82%
Hypoaesthesia (reduced sense of touch or sensation): 4 people, 4.82%
Bipolar Disorder (mood disorder): 4 people, 4.82%

* Approximation only. Some reports may have incomplete information.

Do you take Requip and have Muscle twitching?

- Check whether Muscle twitching is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Requip:

Requip (22,950 reports)

Muscle twitching treatments and more:

Muscle twitching (29,030 reports)

Browse all side effects of Requip:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Muscle twitching:

Muscle twitching (1,238 drugs)

Browse all the conditions that are associated with Muscle twitching:

Muscle twitching (1,905 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on ropinirole hydrochloride (the active ingredients of Requip) and Requip (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.