Restasis and Peripheral vascular disorder - a phase IV clinical study of FDA data

Summary:

Peripheral vascular disorder is reported as a side effect among people who take Restasis (cyclosporine), especially for people who are female, 50-59 old, also take Valium, and have Hypercalcaemia of malignancy.

The phase IV clinical study analyzes which people have Peripheral vascular disorder when taking Restasis. It is created by eHealthMe based on reports of 34,716 people who have side effects when taking Restasis from the FDA, and is updated regularly.

What is Restasis?

Restasis has active ingredients of cyclosporine. It is often used in dry eyes. eHealthMe is studying from 35,199 Restasis users. Check the latest studies of Restasis.

What is Peripheral vascular disorder?

Peripheral vascular disorder is found to be associated with 784 drugs and 758 conditions by eHealthMe. Check the latest studies of Peripheral vascular disorder.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

34,716 people reported to have side effects when taking Restasis.
Among them, 23 people (0.07%) have Peripheral vascular disorder.

Could Restasis cause Peripheral vascular disorder?

Among these 23 people:

What is the gender of people who have Peripheral vascular disorder when taking Restasis? *

female: 95.45 %
male: 4.55 %

What is the age of people who have Peripheral vascular disorder when taking Restasis? *

What are other drugs people take besides Restasis? *

What are other side effects people have besides Peripheral vascular disorder? *

Pain: 19 people, 82.61%
Neuropathy Peripheral (surface nerve damage): 19 people, 82.61%
Hypotension (abnormally low blood pressure): 18 people, 78.26%
Extremity Necrosis (death of body tissue of arms and legs): 18 people, 78.26%
Facial Pain: 18 people, 78.26%
Heart Disease: 18 people, 78.26%
Hip Fracture: 18 people, 78.26%
Hyperkalemia (damage to or disease of the kidney): 18 people, 78.26%
Hyperparathyroidism (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium): 18 people, 78.26%
Hypokalemia (low potassium): 18 people, 78.26%

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 18 people, 78.26%
Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 18 people, 78.26%
Hypercalcaemia (elevated calcium (ca+) level in the blood): 13 people, 56.52%
Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 13.04%
Drowsiness: 3 people, 13.04%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 13.04%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 4.35%
High Blood Pressure: 1 person, 4.35%
High Blood Cholesterol: 1 person, 4.35%
Cushing's Syndrome (obesity, a rounded face, increased fat): 1 person, 4.35%

* Approximation only. Some reports may have incomplete information.

Do you take Restasis and have Peripheral vascular disorder?

- Check whether Peripheral vascular disorder is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Restasis:

Restasis (35,199 reports)

Browse all side effects of Restasis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Peripheral vascular disorder:

Peripheral vascular disorder (784 drugs)

Browse all the conditions that are associated with Peripheral vascular disorder:

Peripheral vascular disorder (758 conditions)

Related publications that referenced our studies

O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .

How the study uses the data?

The study uses data from the FDA. It is based on cyclosporine (the active ingredients of Restasis) and Restasis (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.