Retin-a and Paraesthesia - a phase IV clinical study of FDA data

Summary:

Paraesthesia is reported as a side effect among people who take Retin-a (tretinoin), especially for people who are female, 10-19 old, have been taking the drug for 2 - 5 years also take Doxycycline, and have Depression.

The phase IV clinical study analyzes which people have Paraesthesia when taking Retin-a. It is created by eHealthMe based on reports of 2,373 people who have side effects when taking Retin-a from the FDA, and is updated regularly.

What is Retin-a?

Retin-a has active ingredients of tretinoin. It is often used in acne. eHealthMe is studying from 2,475 Retin-a users. Check the latest studies of Retin-a.

What is Paraesthesia?

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect) is found to be associated with 2,686 drugs and 3,120 conditions by eHealthMe. Check the latest studies of Paraesthesia.

On Jul, 29, 2026

2,373 people reported to have side effects when taking Retin-a.
Among them, 54 people (2.28%) have Paraesthesia.

Among these 54 people:

How long have people been on Retin-a when they have Paraesthesia? *

What is the gender of people who have Paraesthesia when taking Retin-a? *

female: 69.23 %
male: 30.77 %

What is the age of people who have Paraesthesia when taking Retin-a? *

What are other drugs people take besides Retin-a? *

What are other side effects people have besides Paraesthesia? *

Hypoaesthesia (reduced sense of touch or sensation): 15 people, 27.78%
Stress And Anxiety: 14 people, 25.93%
High Blood Cholesterol: 13 people, 24.07%
Muscle Aches (muscle pain): 12 people, 22.22%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 12 people, 22.22%
Joint Pain: 12 people, 22.22%
Patellofemoral Pain Syndrome (pain in the front of the knee): 10 people, 18.52%
Nosebleed (bleeding from nose): 10 people, 18.52%
Joint Dislocation (a joint position is changed from normal position): 10 people, 18.52%
Intervertebral Disc Protrusion (spinal disc protrusion): 10 people, 18.52%

What are the existing conditions these people have? *

Depression: 5 people, 9.26%
Irritable Bowel Syndrome: 4 people, 7.41%
Birth Control: 4 people, 7.41%
Dizziness: 4 people, 7.41%
Migraine (headache): 4 people, 7.41%
Pain: 4 people, 7.41%
Stress And Anxiety: 3 people, 5.56%
Sinus Tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node): 3 people, 5.56%
Dyspnea (difficult or laboured breathing): 3 people, 5.56%
Hair Loss: 3 people, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Retin-a and have Paraesthesia?

- Check whether Paraesthesia is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, long term effects of, and alternative drugs to Retin-a:

Retin-a (2,475 reports)

Paraesthesia treatments and more:

Paraesthesia (184,215 reports)

Browse all side effects of Retin-a:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Paraesthesia:

Paraesthesia (2,686 drugs)

Browse all the conditions that are associated with Paraesthesia:

Paraesthesia (3,120 conditions)

How the study uses the data?

The study uses data from the FDA. It is based on tretinoin (the active ingredients of Retin-a) and Retin-a (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.