Revatio and Increased tendency to bruise - a phase IV clinical study of FDA data

Summary:

Increased tendency to bruise is reported as a side effect among people who take Revatio (sildenafil citrate), especially for people who are female, 60+ old, also take Vitamin D3, and have Gait disturbance.

The phase IV clinical study analyzes which people have Increased tendency to bruise when taking Revatio. It is created by eHealthMe based on reports of 44,758 people who have side effects when taking Revatio from the FDA, and is updated regularly.

What is Revatio?

Revatio has active ingredients of sildenafil citrate. It is often used in pulmonary hypertension. eHealthMe is studying from 44,849 Revatio users. Check the latest studies of Revatio.

What is Increased tendency to bruise?

Increased tendency to bruise (increased tendency to injure the underlying soft tissue or bone) is found to be associated with 768 drugs and 813 conditions by eHealthMe. Check the latest studies of Increased tendency to bruise.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 30, 2026

44,758 people reported to have side effects when taking Revatio.
Among them, 23 people (0.05%) have Increased tendency to bruise.

Could Revatio cause Increased tendency to bruise?

Among these 23 people:

What is the gender of people who have Increased tendency to bruise when taking Revatio? *

female: 52.17 %
male: 47.83 %

What is the age of people who have Increased tendency to bruise when taking Revatio? *

What are other drugs people take besides Revatio? *

What are other side effects people have besides Increased tendency to bruise? *

Dyspnea (difficult or laboured breathing): 16 people, 69.57%
Weakness: 9 people, 39.13%
Oedema Peripheral (superficial swelling): 9 people, 39.13%
Fever: 8 people, 34.78%
Hypoaesthesia (reduced sense of touch or sensation): 8 people, 34.78%
Dizziness: 8 people, 34.78%
Joint Pain: 7 people, 30.43%
Urinary Tract Infection: 7 people, 30.43%
Fatigue (feeling of tiredness): 6 people, 26.09%
High Blood Pressure: 6 people, 26.09%

What are the existing conditions these people have? *

Gait Disturbance: 5 people, 21.74%
Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 4 people, 17.39%
Relapsing-Remitting Multiple Sclerosis (reoccurrence of an inflammatory disease in which the insulating covers of nerve cells in the brain and spinal cord are damaged): 3 people, 13.04%
Dyspnea (difficult or laboured breathing): 3 people, 13.04%
Lung Disorder (lung disease): 2 people, 8.70%
Oedema (fluid collection in tissue): 2 people, 8.70%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 2 people, 8.70%
Muscle Spasms (muscle contraction): 2 people, 8.70%
Movement - Uncoordinated: 2 people, 8.70%
Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 8.70%

* Approximation only. Some reports may have incomplete information.

Do you take Revatio and have Increased tendency to bruise?

- Check whether Increased tendency to bruise is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
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Related studies:

Effectiveness of, long term effects of, and alternative drugs to Revatio:

Revatio (44,849 reports)

Browse all side effects of Revatio:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Increased tendency to bruise:

Increased tendency to bruise (768 drugs)

Browse all the conditions that are associated with Increased tendency to bruise:

Increased tendency to bruise (813 conditions)

Related publications that referenced our studies

Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .
Jeong SY, Jeon SJ, Kim YR, Choi SS, Kwak HS, "A Rare Case of Viagra Induced Toxic Encephalopathy", Investigative Magnetic Resonance Imaging, 2016 Sep .

How the study uses the data?

The study uses data from the FDA. It is based on sildenafil citrate (the active ingredients of Revatio) and Revatio (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.